Multicentric endocrine mucin-producing sweat gland carcinoma and mucinous carcinoma of the skin: a case report. J Cutan Pathol. 2020 Oct 13;: Authors: Nishimoto A, Kuwahara H, Ohashi R, Ansai SI Abstract Endocrine mucin-producing sweat gland carcinoma (EMPSGC) is a rare low-grade sweat gland carcinoma. EMPSGC is thought to be a precursor to mucinous carcinoma of the skin (MCS). Since the first description of EMPSGC in 1997, only a few cases...
Metaplastic breast cancer: Prognostic and therapeutic considerations. J Surg Oncol. 2020 Oct 12;: Authors: Corso G, Frassoni S, Girardi A, De Camilli E, Montagna E, Intra M, Bottiglieri L, Margherita De Scalzi A, Fanianos DM, Magnoni F, Invento A, Toesca A, Conforti F, Bagnardi V, Viale G, Colleoni MA, Veronesi P Abstract INTRODUCTION: Metaplastic breast cancer (MBC) is a rare condition of breast tumor with different subtypes, considered a...
Thoracic Chordoma Misdiagnosed as Primary Adenocarcinoma of the Mediastinum. Korean J Thorac Cardiovasc Surg. 2020 Oct 13;: Authors: Yoon SK, Moon MH, Moon SW Abstract Chordoma is a rare malignant bone tumor originating from the embryonic notochord. Herein, we present a case of thoracic chordoma located at T3-T5 that was misdiagnosed as primary mediastinal adenocarcinoma. The patient underwent neoadjuvant chemoradiation and the disease showed...
[A case of concomitant pancreatic neuroendocrine neoplasm and intraductal papillary mucinous neoplasm in which preoperative diagnosis was difficult]. Nihon Shokakibyo Gakkai Zasshi. 2020;117(10):919-924 Authors: Kusumoto K, Yamazaki Y, Kokuryu H, Itokawa Y, Nakai Y, Azechi H, Fujii S, Kusaka T, Nishitai R, Shibuya S Abstract A 75-year-old male patient has been followed-up for mixed-type intraductal papillary mucinous neoplasm (IPMN) in the...
[Multivisceral resection of lipoblastoma of four anatomical areas of the head and neck with simultaneous neurotization of the facial muscles in an 8-months child. Clinical case]. Stomatologiia (Mosk). 2020;99(5):96-102 Authors: Askerov ED, Topolnitsky OZ, Zayratyants OV, Tsmokalyuk EN, Zhuravleva AV Abstract The article describes diagnostics and surgical treatment of a rare benign tumor (lipoblastoma) of four anatomical areas of the head and...
[Immunohistochemical diagnosis of necrotizing sialometaplasia]. Stomatologiia (Mosk). 2020;99(5):92-95 Authors: Babichenko II, Rabinovich OF, Ivina AA, Semkin VA Abstract The article presents a clinical case of an immunohistochemical study of a rare disease: necrotizing sialometaplasia in the hard palate. Due to the complexity of the differential diagnosis between necrotizing sialometaplasia and squamous cell carcinoma, an immunohistochemical...
Diagnosis of metastatic lung cancer from a colonic polyp: case report of a rare histological diagnosis. N Z Med J. 2020 09 04;133(1521):97-101 Authors: Scowcroft H, Flint R PMID: 32994640 [PubMed - indexed for MEDLINE]
Sarcomatoid hepatocellular carcinoma mimicking hepatic abscess: A case report. Medicine (Baltimore). 2020 Sep 25;99(39):e22489 Authors: Yang Z, Lv K, Zhao Y, Pan M, Zhang C, Wei S Abstract RATIONALE: Primary sarcomatoid hepatocellular carcinoma (SHC) is a rare subtype of morphologic hepatocellular carcinoma reported on less than 1% of surgical pathology specimens. Herein, we report a rare case of SHC. The case in question was initially misdiagnosed...
Usefulness of 99mTc-ASC lymphoscintigraphy and SPECT/CT in the evaluation of rare lymphatic disorders: Gorham-Stout disease, lymphangioma, and lymphangioleiomyomatosis. Medicine (Baltimore). 2020 Sep 25;99(39):e22414 Authors: Hou G, Jiang Y, Jing H, Xu W, Xu KF, Chen L, Li F, Cheng W Abstract The purpose of this study was to investigate the role of Tc-antimony sulfide colloid (ASC) lymphoscintigraphy and single photon emission computed tomography/computed...
First case of bronchiolar adenoma lined purely by mucinous luminal cells with molecular analysis: A case report. Medicine (Baltimore). 2020 Sep 25;99(39):e22322 Authors: Liu S, Liu N, Xiao M, Wang L, Wang EH Abstract RATIONALE: Bronchiolar adenoma (BA) is a newly designated rare entity of the lung, including both the currently designated ciliated muconodular papillary tumor (CMPT) and so-called non-classic CMPT. The most prominent histological...
Osimertinib induced cardiomyopathy: A case report. Medicine (Baltimore). 2020 Sep 25;99(39):e22301 Authors: Shinomiya S, Kaira K, Yamaguchi O, Ishikawa K, Kagamu H Abstract RATIONALE: Cardiotoxicity related to osimertinib, including cardiac failure, QT prolongation, and atrial fibrillation, has been reported as an extremely rare incidence in patients with advanced non-small cell lung cancer (NSCLC). However, little is known about the occurrence...
Related Articles Detection of EP300-ZNF384 fusion in patients with acute lymphoblastic leukemia using RNA fusion gene panel sequencing. Ann Hematol. 2020 Nov;99(11):2611-2617 Authors: Jing Y, Li YF, Wan H, Liu DH Abstract EP300-ZNF384 fusion is a rare recurrent cytogenetic abnormality associated with B cell acute lymphoblastic leukemia (B-ALL), which was rarely studied in Chinese patient cohort. Here, we used a customized RNA fusion gene panel...
Related Articles The peripheral T-cell lymphomas: an unusual path to cure. Lancet Haematol. 2020 Oct;7(10):e765-e771 Authors: Ma H, Marchi E, O'Connor OA Abstract Over the past 30 years, the scientific community has made little progress in changing the natural history of peripheral T-cell lymphomas. Of the haematological malignancies, T-cell lymphomas have an extremely poor prognosis. One reason for this poor outcome has been that no treatment...
Related Articles A Fatal Case of Myocarditis Following Myositis Induced by Pembrolizumab Treatment for Metastatic Upper Urinary Tract Urothelial Carcinoma. Int Heart J. 2020 Sep 29;61(5):1070-1074 Authors: Matsui H, Kawai T, Sato Y, Ishida J, Kadowaki H, Akiyama Y, Yamada Y, Nakamura M, Yamada D, Akazawa H, Suzuki M, Komuro I, Kume H Abstract We report a case of lethal myocarditis and myositis after pembrolizumab treatment for advanced upper...
Related Articles A dedifferentiated intracranial solitary fibrous tumor with osteosarcoma components: rapid tumor progression and lethal clinical course. Brain Tumor Pathol. 2020 Oct;37(4):165-170 Authors: Kambe A, Nakada S, Nagao Y, Uno T, Sakamoto M, Shomori K, Tanabe M, Kondo S, Kurosaki M Abstract Solitary fibrous tumor/hemangiopericytoma is a mesenchymal tumor that originates from a common NAB2-STAT6 fusion gene and is known to very rarely...
Related Articles Cardiac tumors: three decades of experience from a tertiary center: are we changing diagnostic work-up with new imaging tools? Cardiovasc Pathol. 2020 Nov - Dec;49:107242 Authors: Mendes GS, Abecasis J, Ferreira A, Ribeiras R, Abecasis M, Gouveia R, Andrade MJ, Mendes M, Ramos S, Saraiva C, Neves JP Abstract BACKGROUND: Primary cardiac tumours are relatively rare. Cardiac myxomas are the most prevalent and in a significant...
Related Articles Central nervous system neuroepithelial tumors with MN1-alteration: an individual patient data meta-analysis of 73 cases. Brain Tumor Pathol. 2020 Oct;37(4):145-153 Authors: Chen W, Soon YY, Pratiseyo PD, Sutanto R, Hendriansyah L, Kuick CH, Chang KTE, Tan CL Abstract MN1 alteration characterizes a recently described group of neuroepithelial tumors with varied morphological features. In cIMPACT-NOW update 6, only those with...
Related Articles A case of surgically resected cardiac rhabdomyoma with progressive left ventricular outflow tract obstruction. Cardiovasc Pathol. 2020 Nov - Dec;49:107226 Authors: Mohammed F, Tan GC, Hor KN, Arnold M, Wong YP Abstract Cardiac rhabdomyoma is the most prevalent cardiac tumors in the pediatric population, in close association with tuberous sclerosis complex. It is usually detected antenatally or postnatally by echocardiography....
Related Articles Primary Ewing's sarcoma in a small intestine - a case report and review of the literature. BMC Surg. 2020 May 25;20(1):113 Authors: Kolosov A, Dulskas A, Pauza K, Selichova V, Seinin D, Stratilatovas E Abstract BACKGROUND: Ewing's sarcoma usually presents in paediatric patients with its primary location being bone tissue. Nevertheless, we present such an adult case which arises from the small intestine. We registered thirty...
Related Articles Infectious pseudo-aneurysm of the left ventricle: a case report and a review of the literature. BMC Cardiovasc Disord. 2020 03 24;20(1):28 Authors: Juliana AE, van 't Kruys KH, Voigt PG, Blom NA Abstract BACKGROUND: In the workup of a pediatric patient with pericarditis we found evidence of a pseudo-aneurysm of the left ventricle, which is a rare complication of purulent pericarditis. CASE PRESENTATION: We present...
Related Articles A case of primary ovarian signet-ring cell carcinoma treated with S-1/CDDP therapy. J Ovarian Res. 2020 Mar 21;13(1):33 Authors: Shoji T, Takeshita R, Saito T, Aida T, Sasou S, Baba T Abstract BACKGROUND: Primary ovarian signet-ring cell carcinoma is extremely rare, with only five recent case reports. Almost all reported cases of ovarian signet-ring cell carcinoma have been treated with TC therapy and none have reported regarding...
Related Articles [A case of multifocal cavernous haemangiomas of the lung, spleen and bone]. Rev Mal Respir. 2020 Mar;37(3):275-279 Authors: Ancel J, Perotin JM, Dewolf M, Launois C, Hagenburg J, Chouabe S, Lebargy F Abstract INTRODUCTION: Haemangiomas are vascular malformations, frequently cutaneous, hepatic and splenic. Respiratory involvement and multiple localisations are uncommon. CASE REPORT: We present a rare case of multiple...
Related Articles Arenavirus as a potential etiological agent of odontogenic tumours in humans. J Exp Clin Cancer Res. 2020 Feb 10;39(1):34 Authors: de Feo M, De Leo C, Romeo U, Muti P, Blandino G, Di Agostino S Abstract Odontogenic tumors (OT) are considered rare events and their epidemiologic data are scarce and under-estimated in developing countries because there is no systematic collection of clinical features including histological analyses...
Related Articles Editorial: Cholangiocarcinoma - a rare and devastating, but no longer forsaken tumor. Curr Opin Gastroenterol. 2020 03;36(2):55-56 Authors: Housset C PMID: 31895233 [PubMed - indexed for MEDLINE]
Related Articles Cholangiocarcinoma in patients with primary sclerosing cholangitis. Curr Opin Gastroenterol. 2020 03;36(2):77-84 Authors: Fung BM, Tabibian JH Abstract PURPOSE OF REVIEW: Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease characterized by progressive fibroinflammatory destruction of the intrahepatic and/or extrahepatic bile ducts. It is associated with a significantly increased risk of malignancy, particularly...
Related Articles Reply to: Considerations on "impact of centralization of services on outcomes in a rare tumour: Retroperitoneal sarcomas". Eur J Surg Oncol. 2020 04;46(4 Pt A):708 Authors: Kalaiselvan R, Malik AK, Rao R, Wong K, Ali N, Griffin M, Chandrasekar CR, Fenwick SF, Poston GJ, Malik H PMID: 31787426 [PubMed - indexed for MEDLINE]
Related Articles Considerations on "Impact of centralisation of services on outcomes in a rare tumour: Retroperitoneal sarcomas". Eur J Surg Oncol. 2020 04;46(4 Pt A):706-707 Authors: Tirotta F, Desai A, Ford SJ, Strauss DC, Almond LM PMID: 31668979 [PubMed - indexed for MEDLINE]
Related Articles Bleeding signs due to acquired von Willebrand syndrome at diagnosis of chronic myeloid leukaemia in children. Br J Haematol. 2020 03;188(5):701-706 Authors: Knöfler R, Lange BS, Paul F, Tiebel O, Suttorp M Abstract A considerable proportion of patients with chronic myeloid leukaemia (CML) may present at diagnosis with high platelet counts. This may result in thrombosis or bleeding complications due to binding of von Willebrand...
Related Articles Safety and Costs of Endobronchial Ultrasound-Guided Nodal Aspiration and Mediastinoscopy. Chest. 2020 03;157(3):686-693 Authors: Verdial FC, Berfield KS, Wood DE, Mulligan MS, Roth JA, Francis DO, Farjah F Abstract BACKGROUND: There remains debate over the best invasive diagnostic modality for mediastinal nodal evaluation. Prior studies have limited generalizability and insufficient power to detect differences in rare adverse...
Related Articles An upsurge of the serum free light chains as a possible missing link in tumour lysis syndrome in multiple myeloma. Br J Haematol. 2020 03;188(5):732-735 Authors: Yavorkovsky LL, Jing W, Baker R Abstract Multiple myeloma (MM) is a slow-growing malignancy characterized by a low proliferation rate of plasma cells and a relatively rare incidence of tumour lysis syndrome (TLS). Three myeloma patients developed TLS following cytotoxic...
Related Articles Loss of Janus Associated Kinase 1 Alters Urothelial Cell Function and Facilitates the Development of Bladder Cancer. Front Immunol. 2019;10:2065 Authors: Daza-Cajigal V, Albuquerque AS, Pearson J, Hinley J, Mason AS, Stahlschmidt J, Thrasher AJ, Mishra V, Southgate J, Burns SO Abstract Inherited Primary Immunodeficiency (PID) disorders are associated with increased risk of malignancy that may relate to impaired antitumor immune...
Related Articles Diagnosis of hepatocellular adenoma in men before onset of diabetes in HNF1A-MODY: Watch out for winkers. Liver Int. 2019 11;39(11):2042-2045 Authors: Haring MPD, Vriesendorp TM, Klein Wassink-Ruiter JS, de Haas RJ, Gouw ASH, de Meijer VE Abstract Hepatocyte nuclear factor 1A (HNF1A) maturity-onset diabetes of the young (MODY) is a monogenetic, autosomal dominantly inherited form of diabetes. HNF1A-MODY is associated with...
Related Articles Laser-induced plasmon-mediated treatment of retinoblastoma in viscous vitreous phantom. J Biophotonics. 2019 11;12(11):e201900193 Authors: Darviot C, Hardy P, Meunier M Abstract Retinoblastoma (RB) is a rare form of cancer of the retina most prevalent in young children. We successfully show that laser-induced cell disruption, mediated by gold plasmonic nanoparticle (NP), is a potential and efficient therapy to kill the cancerous...
Related Articles Chest wall lump: lipoma or intramuscular myxoma? Gen Thorac Cardiovasc Surg. 2020 May;68(5):546-548 Authors: Raniwsky A, Schmidt M, Eid JJ, Lee MW Abstract Intramuscular myxomas (IM) of the chest wall are extremely rare. We present the case of a 58-year-old African-American female who was initially diagnosed with having a chest wall lipoma. After re-evaluation, the lesion was consistent with an intercostal myxoma versus myxoid...
Related Articles Dermatofibrosarcoma protuberans: our 10-year experience on 80 patients. J Dermatolog Treat. 2020 Sep;31(6):554-558 Authors: Zhou X, Sun D, Liu Y, Sun Q, Yuan Z, Luo X, Yang J, Chen J Abstract Background: Dermatofibrosarcoma protuberans (DFSP) is a rare soft tissue sarcoma. Its high recurrence rate is a clinical challenge.Objective: To analyze DFSP clinicopathologic factors and review our experience of treatments.Materials and...
Related Articles Efficacy of the novel CDK7 inhibitor QS1189 in mantle cell lymphoma. Sci Rep. 2019 05 10;9(1):7193 Authors: Choi YJ, Kim DH, Yoon DH, Suh C, Choi CM, Lee JC, Hong JY, Rho JK Abstract Mantle cell lymphoma (MCL) is typically an aggressive and rare form of non-Hodgkin lymphoma (NHL) with a poor prognosis despite recent advances in immunochemotherapy and targeted therapeutics against NHL. New therapeutic agents are needed for...
Related Articles Predisposition of Wingless Subgroup Medulloblastoma for Primary Tumor Hemorrhage. Neurosurgery. 2020 04 01;86(4):478-484 Authors: Reisinger D, Gojo J, Kasprian G, Haberler C, Peyrl A, Azizi AA, Mayr L, Chocholous M, Kool M, Czech T, Slavc I Abstract BACKGROUND: Primary intratumoral hemorrhage as a presenting sign is rare in children with medulloblastomas but may result in severe complications. Given the distinct properties...
Related Articles Cervical intradural extramedullary epidermoid cyst at the background of congenital scoliosis with a semi-segmented C6 hemivertebra. Childs Nerv Syst. 2019 08;35(8):1411-1413 Authors: Turgut VU, Ekşi MŞ, Özak A, Özcan-Ekşi EE Abstract In the present case study, we present a female adolescent patient harboring a rare clinical presentation of spinal intradural extramedullary epidermoid cyst concomitant with congenital scoliosis....
Related Articles Pediatric Intracavernous Sinus Lesions: A Single Institutional Surgical Case Series and Review of the Literature. Oper Neurosurg (Hagerstown). 2019 10 01;17(4):354-364 Authors: Hoshide R, Rennert RC, Calayag M, Gonda D, Meltzer H, Crawford JR, Levy ML Abstract BACKGROUND: Pediatric intracavernous sinus tumors are exceedingly rare and thus poorly characterized. Their neurosurgical management is challenging and diagnostic, and...
Related Articles Mycotic Aneurysm of the Ulnar Artery Secondary to Bacillus Calmette-Guérin Therapy for Bladder Cancer: A Rare Presentation of Hypothenar Hammer Syndrome. J Hand Surg Am. 2019 Oct;44(10):905.e1-905.e4 Authors: Jorgensen MS, Oldenburg WA, Murray PM Abstract Mycotic aneurysms, especially those of the upper extremity, are rarely reported in literature. These aneurysms are caused by bacterial endocarditis and, therefore, are more...
Related Articles Malignant mesothelioma of the tunica vaginalis: a atypical presentation of a rare scrotal tumour. ANZ J Surg. 2019 12;89(12):E562-E563 Authors: Harris MC, Logan C, Chetwood A, Cohen P, Titus J, Tan TH, Higgs B, Brook NR PMID: 30706607 [PubMed - indexed for MEDLINE]
Related Articles A Rare Case of Hyperplastic Proximal Esophageal Polyps With Foveolar Dysplasia. Clin Gastroenterol Hepatol. 2019 06;17(7):e75-e76 Authors: Hayat M, Mahmood S, Maple JT PMID: 29902643 [PubMed - indexed for MEDLINE]
Pembrolizumab and other immune checkpoint inhibitors in locally advanced or metastatic merkel cell carcinoma: safety and efficacy. Expert Rev Anticancer Ther. 2020 Oct 12;: Authors: Marchand A, Kervarrec T, Bhatia S, Samimi M Abstract INTRODUCTION: Merkel Cell Carcinoma (MCC) is a rare aggressive skin cancer, mostly affecting elderly patients. Until recently, patients with advanced disease were treated with cytotoxic chemotherapies despite...
Unilateral Maxillary Sinus Plasmablastic Lymphoma in an Immunocompetent Patient. An Unusual Occurrence Report and Literature Review. Ear Nose Throat J. 2020 Oct 12;:145561320963715 Authors: Chicuellar NR, Sufyan W, Mahendran S Abstract Plasmablastic lymphoma (PBL) is a rare and aggressive form of mature B cell neoplasms almost exclusively identified in patients infected with the human immunodeficiency virus (HIV). The small number of HIV-negative...
Adenomatous neuroendocrine tumors of the middle ear (MEANTs) with local invasion and lymph nodes metastasis: A brief report of a rare neoplasm. Diagn Cytopathol. 2020 Oct 12;: Authors: Yang L, Asiry S, Khader SN Abstract Adenomatous neuroendocrine tumors of the middle ear (MEANTs) are very rare neoplasms which are composed of both epithelial and neuroendocrine components. They have mostly bland histology and indolent biological behavior, yet...
The frequency and malignancy rate of incidental focal breast lesions identified by 18F-fluorodeoxyglucose positron emission tomography. Nucl Med Commun. 2020 Oct 09;: Authors: Andersen JD, Zacho HD, Petersen LJ Abstract OBJECTIVE: To evaluate the frequency and malignancy rate of incidental focal uptake of 18F-fluorodeoxyglucose (FDG) in the breast on PET/computed tomography (CT). MATERIAL AND METHODS: All PET/CT scan reports from a...
SETD8C302R Mutation Revealed from Myofibroblastoma-Discordant Monozygotic Twins Leads to p53/p21 Deficit and WEE1 Inhibitor Sensitivity. Adv Sci (Weinh). 2020 Oct;7(19):2001041 Authors: Li M, Wang H, Liao H, Shen J, Wu Y, Wu Y, Weng Q, Zhu C, Geng X, Lan F, Xia Y, Zhang B, Zou H, Zhang N, Zhou Y, Chen Z, Shen H, Ying S, Li W Abstract High-throughput gene sequencing has identified various genetic variants as the culprits for some common hereditary...
Bronchial Fibroepithelial Polyp With Severe Hemoptysis as First Manifestation: A Case Report. Cureus. 2020 Sep 05;12(9):e10261 Authors: Georgakopoulou VE, Kourtelesi E, Mermigkis D, Trakas N, Tsiafaki X Abstract Fibroepithelial polyps are uncommon benign tumors that mostly occur in skin, oral cavity and genitourinary tract. These lesions have common morphological features with other mesenchymal tumors such as angiomyofibroblastoma, aggressive...
Primary Gastrointestinal Stromal Tumor of the Prostate: Unexpected Guest. Cureus. 2020 Sep 04;12(9):e10244 Authors: Al-Maghrabi H, Alahmadi S, Falemban AH Abstract Primary mesenchymal lesions of the prostate are exceptionally rare. They comprise 1% of all prostatic neoplasms. Despite its rare location, the diagnosis of primary gastrointestinal stromal tumors (GISTs) of the prostate gland should never be missed. Such a diagnosis can be made...
Pancreatic metastasis from non-small cell lung carcinoma diagnosed on EUS biopsy: report of a rare case and potential pitfall. Int J Clin Exp Pathol. 2020;13(9):2412-2414 Authors: Wu PS Abstract Lung non-small cell carcinoma is one of the most common cancers in the world. Pancreas metastasis from lung cancer is very rare. Endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNAB) is a useful method to improve the diagnosis of pancreatic...
Prepubertal-type teratoma in a postpubertal patient: case report and review of literature. Int J Clin Exp Pathol. 2020;13(9):2407-2411 Authors: Jiang D, Yang X, Ding M, Liao G, Zhu J, Wang X, Pang J, Li J Abstract Prepubertal-type teratomas are rare, especially in postpubertal patients. We present a case of a 43-year-old man with a palpable painless mass in the left-sided testis discovered by accident. Scrotal ultrasound and magnetic resonance...
Rapidly growing giant solitary fibrous tumor of the pleura: a case report and review of the literature. Int J Clin Exp Pathol. 2020;13(9):2363-2368 Authors: Wang Y, Xu Y, Li R, Yuan Y Abstract Solitary fibrous tumors of the pleura (SFTPs) are rare slowly-growing tumors that originate from mesenchymal cells of the submesothelial tissue of the pleura. A 57-year-old female presented to our institute, and complained of mild chest discomfort for...
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