Antioxidants, Vol. 9, Pages 471: AOP1, a New Live Cell Assay for the Direct and Quantitative Measure of Intracellular Antioxidant Effects Antioxidants doi: 10.3390/antiox9060471 Authors: Gironde Rigal Dufour Furger Taking advantage of Light Up Cell System (LUCS) technology, which allows for fine monitoring of reactive oxygen species (ROS) production inside live cells, a new assay called Anti Oxidant Power 1 (AOP1) was developed to specifically measure ROS and/or free-radical...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 466: An Environmentally Friendly Practice Used in Olive Cultivation Capable of Increasing Commercial Interest in Waste Products from Oil Processing Antioxidants doi: 10.3390/antiox9060466 Authors: Dini Graziani Fedele Sicari Vinale Castaldo Ritieni In the Rural Development Plan (2014–2020), the European Commission encouraged the conversion and supported the maintenance of organic farming. Organic olive oil (bioEVOO) production...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 470: Anti-Migratory Effects of 4′-Geranyloxyferulic Acid on LPS-Stimulated U937 and HCT116 Cells via MMP-9 Down-Regulation: Involvement of ROS/ERK Signaling Pathway Antioxidants doi: 10.3390/antiox9060470 Authors: Sara Franceschelli Daniela Maria Pia Gatta Alessio Ferrone Giulia Mezza Lorenza Speranza Mirko Pesce Alfredo Grilli Marialucia Gallorini Viviana Di Giacomo Barbara Ghinassi Serena Fiorito Salvatore Genovese Emanuela...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 468: When Oxidative Stress Meets Epigenetics: Implications in Cancer Development Antioxidants doi: 10.3390/antiox9060468 Authors: García-Guede Vera Ibáñez-de-Caceres Cancer is one of the leading causes of death worldwide and it can affect any part of the organism. It arises as a consequence of the genetic and epigenetic changes that lead to the uncontrolled growth of the cells. The epigenetic machinery can regulate gene expression without altering...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 467: Fe Porphyrin-Based SOD Mimic and Redox-Active Compound, (OH)FeTnHex-2-PyP4+, in a Rodent Ischemic Stroke (MCAO) Model: Efficacy and Pharmacokinetics as Compared to Its Mn Analogue, (H2O)MnTnHex-2-PyP5+ Antioxidants doi: 10.3390/antiox9060467 Authors: Li Tovmasyan Sheng Xu Sampaio Reboucas Warner Batinic-Haberle Spasojevic Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, (H2O)MnTnHex-2-PyP5+ (MnHex) carrying long...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 469: Screening of Natural Stilbene Oligomers from Vitis vinifera for Anticancer Activity on Human Hepatocellular Carcinoma Cells Antioxidants doi: 10.3390/antiox9060469 Authors: Iris Aja M. Begoña Ruiz-Larrea Arnaud Courtois Stéphanie Krisa Tristan Richard José-Ignacio Ruiz-Sanz The characterization of bioactive resveratrol oligomers extracted from Vitis vinifera canes has been recently reported. Here, we screened six of these compounds (ampelopsin...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 465: Species-Specific, pH-Independent, Standard Redox Potential of Selenocysteine and Selenocysteamine Antioxidants doi: 10.3390/antiox9060465 Authors: Tamás Pálla Arash Mirzahosseini Béla Noszál Microscopic redox equilibrium constants and standard redox potential values were determined to quantify selenolate-diselenide equilibria of biological significance. The highly composite, codependent acid-base and redox equilibria of selenolates could so far...
Mon Jun 01, 2020 03:00
Antioxidants, Vol. 9, Pages 464: Reply to Comment on “Differential Effects of MitoVitE, α-Tocopherol and Trolox on Oxidative Stress, Mitochondrial Function and Inflammatory Signalling Pathways in Endothelial Cells Cultured under Conditions Mimicking Sepsis. Antioxidants 2020, 9(3), 195” Antioxidants doi: 10.3390/antiox9060464 Authors: Beverley E. Minter Damon A. Lowes Nigel R. Webster Helen F. Galley We thank Drs Hegarty and Byrne for their interest in our paper and appreciate...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 579: Connection Between Antarctic Ozone and Climate: Interannual Precipitation Changes in the Southern Hemisphere Atmosphere doi: 10.3390/atmos11060579 Authors: Damiani Cordero Llanillo Feron Boisier Garreaud Rondanelli Irie Watanabe In this study, we explored the connection between anomalies in springtime Antarctic ozone and all-year precipitation in the Southern Hemisphere by using observations from 1960–2018 and...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 577: Retrospective Analysis of Tree Decline Based on Intrinsic Water-Use Efficiency in Semi-Arid Areas of North China Atmosphere doi: 10.3390/atmos11060577 Authors: Lu Yu Jia Long-term tree growth is significantly affected by climate change, which have become a global concern. Tree-ring width and isotopic information can show how trees respond to climate change on a long-term scale and reveal some phenomena of tree decline or death. In this study,...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 576: Improved Simulation of the Antarctic Stratospheric Final Warming by Modifying the Orographic Gravity Wave Parameterization in the Beijing Climate Center Atmospheric General Circulation Model Atmosphere doi: 10.3390/atmos11060576 Authors: Yixiong Lu Tongwen Wu Xin Xu Li Zhang Min Chu The Antarctic stratospheric final warming (SFW) is usually simulated with a substantial delay in climate models, and the corresponding temperatures in austral spring...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 578: Drop Size Distribution Measurements in Outer Rainbands of Hurricane Dorian at the NASA Wallops Precipitation-Research Facility Atmosphere doi: 10.3390/atmos11060578 Authors: Thurai Bringi Wolff Marks Pabla Hurricane rainbands are very efficient rain producers, but details on drop size distributions are still lacking. This study focuses on the rainbands of hurricane Dorian as they traversed the densely instrumented NASA precipitation-research...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 575: Model Details, Parametrization, and Accuracy in Daily Scale Green Roof Hydrological Conceptual Simulation Atmosphere doi: 10.3390/atmos11060575 Authors: Mirka Mobilia Antonia Longobardi In time, several models with different complexity have been proposed to predict the retention performances of a green roof. In the current study three conceptual models of increasing complexity in descriptive details, are calibrated and compared to experimental data....
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 573: The Influence of Graphene Oxide on Nanoparticle Emissions during Drilling of Graphene/Epoxy Carbon-Fiber Reinforced Engineered Nanomaterials Atmosphere doi: 10.3390/atmos11060573 Authors: Kristof Starost James Njuguna Graphene oxide (GO) nanoparticles are increasingly being used to tailor industrial composites. However, despite the advantages, GO has shown conceivable health risks and toxicity to humans and the environment if released. This study investigates...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 574: Preliminary Tests on the Sensitivity of the FORAIR_IT Air Quality Forecasting System to Different Meteorological Drivers Atmosphere doi: 10.3390/atmos11060574 Authors: Adani Piersanti Ciancarella D’Isidoro Villani Vitali Since 2017, the operational high-resolution air quality forecasting system FORAIR_IT, developed and maintained by the Italian National Agency for New Technologies, Energy and Sustainable Economic Development, has been...
Mon Jun 01, 2020 03:00
Atmosphere, Vol. 11, Pages 572: Chemical Analysis of Surface-Level Ozone Exceedances during the 2015 Pan American Games Atmosphere doi: 10.3390/atmos11060572 Authors: Stroud Ren Zhang Moran Akingunola Makar Munoz-Alpizar Leroyer Bélair Sills Brook Surface-level ozone (O3) continues to be a significant health risk in the Greater Toronto Hamilton Area (GTHA) of Canada even though precursor emissions in the area have decreased significantly over...
Mon Jun 01, 2020 03:00
Beverages, Vol. 6, Pages 36: Dynamic of Lachancea thermotolerans Population in Monoculture and Mixed Fermentations: Impact on Wine Characteristics Beverages doi: 10.3390/beverages6020036 Authors: Pilar Blanco Eva Rabuñal Noemi Neira David Castrillo Lachancea thermotolerans is a non-Saccharomyces yeast appreciated for its potential of acidification due to the production of lactic acid; however, this species also synthetizes other metabolites that modulate organoleptic wine properties....
Mon Jun 01, 2020 03:00
Beverages, Vol. 6, Pages 35: Happy Hour? A Preliminary Study of the Effect of Induced Joviality and Sadness on Beer Perception Beverages doi: 10.3390/beverages6020035 Authors: Beth Desira Shaun Watson George Van Doorn Justin Timora Charles Spence Our emotions influence our perception. In order to determine whether emotion influences the perception of beer, 32 participants watched either a scene from the movie Wall-E to induce joviality, or a short clip from the Shawshank...
Mon Jun 01, 2020 03:00
Biomedicines, Vol. 8, Pages 147: Transcriptome-Wide Analysis of CXCR5 Deficient Retinal Pigment Epithelial (RPE) Cells Reveals Molecular Signatures of RPE Homeostasis Biomedicines doi: 10.3390/biomedicines8060147 Authors: Madhu Sudhana Saddala Anton Lennikov Anthony Mukwaya Hu Huang Age-related macular degeneration (AMD) is the most common cause of irreversible blindness in the elderly population. In our previous studies, we found that deficiency of CXCR5 causes AMD-like pathological...
Mon Jun 01, 2020 03:00
Biomedicines, Vol. 8, Pages 146: Probiotics-Containing Yogurt Ingestion and H. pylori Eradication Can Restore Fecal Faecalibacterium prausnitzii Dysbiosis in H. pylori-Infected Children Biomedicines doi: 10.3390/biomedicines8060146 Authors: Yao-Jong Yang Peng-Chieh Chen Fu-Ping Lai Pei-Jane Tsai Bor-Shyang Sheu This study investigated the compositional differences in fecal microbiota between children with and without H. pylori infection and tested whether probiotics-containing...
Mon Jun 01, 2020 03:00
Biomolecules, Vol. 10, Pages 844: Effects of Flavanols on Enteroendocrine Secretion Biomolecules doi: 10.3390/biom10060844 Authors: Carme Grau-Bové Carlos González-Quilen Ximena Terra M Teresa Blay Raul Beltrán-Debón Rosa Jorba-Martín Beatriz Espina Montserrat Pinent Anna Ardévol Some beneficial effects of grape seed proanthocyanidin extract (GSPE) can be explained by the modulation of enterohormone secretion. As GSPE comprises a combination of different molecules,...
Mon Jun 01, 2020 03:00
Brain Sciences, Vol. 10, Pages 337: Hand Fine Motor Skill Disability Correlates with Cognition in Patients with Moderate-to-Advanced Parkinson’s Disease Brain Sciences doi: 10.3390/brainsci10060337 Authors: Shennie Tan Chien Tai Hong Jia-Hung Chen Lung Chan Wen-Chou Chi Chia-Feng Yen Hua-Fang Liao Tsan-Hon Liou Dean Wu In older individuals, hand fine motor skill disability is associated with cognitive levels. Similarly, patients with moderate-to-advanced Parkinson’s...
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Cancers, Vol. 12, Pages 1444: Impact of CD56 Continuously Recognizable as Prognostic Value of Acute Promyelocytic Leukemia: Results of Multivariate Analyses in the Japan Adult Leukemia Study Group (JALSG)-APL204 Study and a Review of the Literature Cancers doi: 10.3390/cancers12061444 Authors: Takeshita Asou Atsuta Furumaki Sakura Ueda Sawa Dobashi Taniguchi Suzuki Nakagawa Tamaki Hagihara Fujimaki Minamiguchi Fujita Yanada ...
Mon Jun 01, 2020 03:00
Cancers, Vol. 12, Pages 1443: Biomarker Panel for the Diagnosis of Pancreatic Ductal Adenocarcinoma Cancers doi: 10.3390/cancers12061443 Authors: Hongbeom Kim Kyung Nam Kang Yong Sung Shin Yoonhyeong Byun Youngmin Han Wooil Kwon Chul Woo Kim Jin-Young Jang A single tumor marker has a low diagnostic value in pancreatic cancer. Combinations of multiple biomarkers and unique analysis algorithms can be applied to overcome these limitations. This study sought to develop...
Mon Jun 01, 2020 03:00
Cancers, Vol. 12, Pages 1442: Improving Multi-Tumor Biomarker Health Check-up Tests with Machine Learning Algorithms Cancers doi: 10.3390/cancers12061442 Authors: Hsin-Yao Wang Chun-Hsien Chen Steve Shi Chia-Ru Chung Ying-Hao Wen Min-Hsien Wu Michael S. Lebowitz Jiming Zhou Jang-Jih Lu Background: Tumor markers are used to screen tens of millions of individuals worldwide at annual health check-ups, especially in East Asia. Machine learning (ML)-based algorithms...
Mon Jun 01, 2020 03:00
Cancers, Vol. 12, Pages 1439: SPON2 Is Upregulated through Notch Signaling Pathway and Promotes Tumor Progression in Gastric Cancer Cancers doi: 10.3390/cancers12061439 Authors: Hyeon-Gu Kang Won-Jin Kim Myung-Giun Noh Kyung-Hee Chun Seok-Jun Kim Spondin-2 (SPON2) is involved in cancer progression and metastasis of many tumors; however, its role and underlying mechanism in gastric cancer are still obscure. In this study, we investigated the role of SPON2 and related signaling...
Mon Jun 01, 2020 03:00
Cancers, Vol. 12, Pages 1441: A Germline Mutation in the POT1 Gene Is a Candidate for Familial Non-Medullary Thyroid Cancer Cancers doi: 10.3390/cancers12061441 Authors: Aayushi Srivastava Beiping Miao Diamanto Skopelitou Varun Kumar Abhishek Kumar Nagarajan Paramasivam Elena Bonora Kari Hemminki Asta Försti Obul Reddy Bandapalli Non-medullary thyroid cancer (NMTC) is a common endocrine malignancy with a genetic basis that has yet to be unequivocally established....
Mon Jun 01, 2020 03:00
Cancers, Vol. 12, Pages 1440: Metabolic Profiling of Early and Late Recurrent Pancreatic Ductal Adenocarcinoma Using Patient-Derived Organoid Cultures Cancers doi: 10.3390/cancers12061440 Authors: Lukas M. Braun Simon Lagies Rhena F. U. Klar Saskia Hussung Ralph M. Fritsch Bernd Kammerer Uwe A. Wittel Pancreatic ductal adenocarcinoma (PDAC) is associated with high mortality and will become the second most common cause of cancer-associated mortality by 2030. The poor...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1377: Comparison of Multiscale Imaging Methods for Brain Research Cells doi: 10.3390/cells9061377 Authors: Jessica Tröger Christian Hoischen Birgit Perner Shamci Monajembashi Aurélien Barbotin Anna Löschberger Christian Eggeling Michael M. Kessels Britta Qualmann Peter Hemmerich A major challenge in neuroscience is how to study structural alterations in the brain. Even small changes in synaptic composition could have severe outcomes for...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1376: PD-1: Its Discovery, Involvement in Cancer Immunotherapy, and Beyond Cells doi: 10.3390/cells9061376 Authors: Yasumasa Ishida On December 10, 2018, I was sitting among the big crowd of audience, as one of the invited guests to the ceremony, in the Stockholm Concert Hall. When King of Sweden Carl XVI Gustaf bestowed the diploma and medal of Nobel Prize of Physiology or Medicine 2018 on Dr. Tasuku Honjo and shook his hand for a while, surrounded by the thunderous...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1374: Early Reperfusion Following Ischemic Stroke Provides Beneficial Effects, Even After Lethal Ischemia with Mature Neural Cell Death Cells doi: 10.3390/cells9061374 Authors: Yasue Tanaka Nami Nakagomi Nobutaka Doe Akiko Nakano-Doi Toshinori Sawano Toshinori Takagi Tomohiro Matsuyama Shinichi Yoshimura Takayuki Nakagomi Ischemic stroke is a critical disease caused by cerebral artery occlusion in the central nervous system (CNS). Recent therapeutic...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1373: Effects of β-Adrenergic Blockade on Metabolic and Inflammatory Responses in a Rat Model of Ischemic Stroke Cells doi: 10.3390/cells9061373 Authors: Shih-Yi Lin Ya-Yu Wang Cheng-Yi Chang Chih-Cheng Wu Wen-Ying Chen Yu-Hsiang Kuan Su-Lan Liao Chun-Jung Chen Ischemic stroke provokes an inflammatory response concurrent with both sympathetic nervous system activation and hyperglycemia. Currently, their crosstalk and consequences in stroke outcomes...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1375: Fructose 1,6-Bisphosphatase 2 Plays a Crucial Role in the Induction and Maintenance of Long-Term Potentiation Cells doi: 10.3390/cells9061375 Authors: Przemysław Duda Tomasz Wójtowicz Jakub Janczara Daniel Krowarsch Aleksandra Czyrek Agnieszka Gizak Dariusz Rakus Long-term potentiation (LTP) is a molecular basis of memory formation. Here, we demonstrate that LTP critically depends on fructose 1,6-bisphosphatase 2 (Fbp2)—a glyconeogenic...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1370: Biomarkers in Hepatocellular Carcinoma: Diagnosis, Prognosis and Treatment Response Assessment Cells doi: 10.3390/cells9061370 Authors: Federico Piñero Melisa Dirchwolf Mário G. Pessôa Hepatocellular carcinoma (HCC) is one of the main cancer-related causes of death worldwide. Thus, there is a constant search for improvement in screening, diagnosis, and treatment strategies to improve the prognosis of this malignancy. The identification of useful biomarkers...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1371: Intrinsic Abnormalities of Cystic Fibrosis Airway Connective Tissue Revealed by an In Vitro 3D Stromal Model Cells doi: 10.3390/cells9061371 Authors: Claudia Mazio Laura S. Scognamiglio Rossella De Cegli Luis J.V. Galietta Diego Di Bernardo Costantino Casale Francesco Urciuolo Giorgia Imparato Paolo A. Netti Cystic fibrosis is characterized by lung dysfunction involving mucus hypersecretion, bacterial infections, and inflammatory response....
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1368: Insulin-like Growth Factor-1 and IGF Binding Proteins Predict All-Cause Mortality and Morbidity in Older Adults Cells doi: 10.3390/cells9061368 Authors: William B. Zhang Sandra Aleksic Tina Gao Erica F. Weiss Eleni Demetriou Joe Verghese Roee Holtzer Nir Barzilai Sofiya Milman While the growth hormone/insulin-like growth factor-1 (GH/IGF-1) pathway plays essential roles in growth and development, diminished signaling via this pathway...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1369: Resistin Enhances VCAM-1 Expression and Monocyte Adhesion in Human Osteoarthritis Synovial Fibroblasts by Inhibiting MiR-381 Expression through the PKC, p38, and JNK Signaling Pathways Cells doi: 10.3390/cells9061369 Authors: Wei-Cheng Chen Chih-Yang Lin Shu-Jui Kuo Shan-Chi Liu Yung-Chang Lu Yen-Ling Chen Shih-Wei Wang Chih-Hsin Tang The development of osteoarthritis (OA) is characterized by synovial inflammation and the upregulation of...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1372: Adenosine A2AReceptors in Substance Use Disorders: A Focus on Cocaine Cells doi: 10.3390/cells9061372 Authors: Karolina Wydra Dawid Gawliński Kinga Gawlińska Małgorzata Frankowska Dasiel O. Borroto-Escuela Kjell Fuxe Małgorzata Filip Several psychoactive drugs can evoke substance use disorders (SUD) in humans and animals, and these include psychostimulants, opioids, cannabinoids (CB), nicotine, and alcohol. The etiology, mechanistic processes,...
Mon Jun 01, 2020 03:00
Cells, Vol. 9, Pages 1364: A Role for mir-26a in Stress: A Potential sEV Biomarker and Modulator of Excitatory Neurotransmission Cells doi: 10.3390/cells9061364 Authors: Carlos Andrés Lafourcade Anllely Fernández Juan Pablo Ramírez Katherine Corvalán Miguel Ángel Carrasco Andrés Iturriaga Luis Federico Bátiz Alejandro Luarte Ursula Wyneken Stress is a widespread problem in today’s societies, having important consequences on brain function. Among the...
Mon Jun 01, 2020 03:00
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