This study presents a novel methodology to investigate the nonparametric estimation of a survival probability under random censoring time using the ranked observations from a Partially Rank-Ordered Set (PROS) sampling design and employs it in a hematological disorder study. The PROS sampling design has numerous applications in medicine, social sciences and ecology where the exact measurement of the sampling units is costly; however, sampling units can be ordered by using judgment ranking or available...
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The purpose of this study was to investigate the variations of arch index from static standing to dynamic walking and running; furthermore, the interlimb symmetry was checked in the two populations. A total of eighty male participants were recruited for this study, with forty habitually barefoot and forty habitually shod males, respectively. Arch index (AI) was calculated following the previously established “gold standard” measurement via contact areas recorded from EMED. Repeated measure analysis...
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To deal with coordination problem of a supply chain consisting of two competitive suppliers and a dominant retailer, considering these factors such as cooperation effort degrees and competition on the supply chain members, we establish a two-stage model considering cooperation effort degrees and competition of the suppliers from the perspectives of decentralized decision and centralized decision and exploit it to discuss the optional decisions and explore the impact of cooperation effort degrees...
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Background. Early sickle cell disease (SCD) diagnosis has shown promise in combating SCD in many countries. The aim of this study was to assess the practice and perception of early SCD diagnosis among a group of parents and physicians in Nigeria. Patients and Methods. This was a cross-sectional descriptive study conducted to assess the opinions and practice of early diagnosis of SCD among 135 physicians caring for SCD patients and 164 mothers of children with SCD in a southwestern state of Nigeria....
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Cell proliferation and angiogenesis are of utmost importance for healing to take place. The KI67 and EGFR proteins are markers of cell proliferation, while CD31 and factor VIII are markers of angiogenesis. To elucidate the mechanism responsible for delayed healing of the gastric injury in old age, we analyzed the expression of these markers in rats of different months during the healing of an acetic acid-induced gastric ulcer. Male Wistar rats (aged 3, 6, 12, and 18 months) divided into four groups,...
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Let be positive integers. By definition, is the least positive integer such that, for any -coloring of the interval , there exists a monochromatic solution to . For , the numbers are classical Schur numbers. In this paper, we study the numbers for .
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In this paper, new notions of the weighted core-EP left inverse and the weighted MPD inverse which are dual to the weighted core-EP (right) inverse and the weighted DMP inverse, respectively, are introduced and represented. The direct methods of computing the weighted right and left core-EP, DMP, MPD, and CMP inverses by obtaining their determinantal representations are given. A numerical example to illustrate the main result is given.
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To advance the study of lip-reading recognition in accordance with Chinese pronunciation norms, we carefully investigated Mandarin tone recognition based on visual information, in contrast to that of the previous character-based Chinese lip reading technique. In this paper, we mainly studied the vowel tonal transformation in Chinese pronunciation and designed a lightweight skipping convolution network framework (SCNet). And, the experimental results showed that the SCNet was sensitive to the more...
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In this paper, a three-dimensional path planning problem of an unmanned aerial vehicle under constant thrust is studied based on the artificial fluid method. The effect of obstacles on the original fluid field is quantified by the perturbation matrix, the streamlines can be regarded as the planned path for the unmanned aerial vehicle, and the tangential vector and the disturbance matrix of the artificial fluid method are improved. In particular, this paper addresses a novel algorithm of constant...
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According to the information reflected by Anhui Center for Disease Control (Anhui CDC) in Hefei, Anhui province of China, some patients infected with respiratory diseases did not seek medical treatment (nonclinic visits) due to their strong resistance, and the influence of them on the spread of respiratory diseases has not been known. A SIS model with considering the nonclinic visits was established; a qualitative theory of the model was analyzed to obtain the basic reproduction number , disease-free...
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Recommendation of a relevant and suitable news article is an essential but a challenging task due to changes in the user interest categories over time. Moreover, the Internet technology provides abundant news articles from a huge amount of resources. Meanwhile, nowadays, many people are confronted with viral news articles through social media cost-free without considering the news sites. Therefore, mining of social media for addressing such viral news articles has become another key challenge. To...
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The prediction of stock excess returns is an important research topic for quantitative trading, and stock price prediction based on machine learning is receiving more and more attention. This article takes the data of Chinese A-shares from July 2014 to September 2017 as the research object, and proposes a method of stock excess return forecasting that combines research reports and investor sentiment. The proposed method measures individual stocks released by analysts, separates the two indicators...
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Sensitive data need to be protected from being stolen and read by unauthorized persons regardless of whether the data are stored in hard drives, flash memory, laptops, desktops, and other storage devices. In an enterprise environment where sensitive data is stored on storage devices, such as financial or military data, encryption is used in the storage device to ensure data confidentiality. Nowadays, the SSD-based NAND storage devices are favored over HDD and SSHD to store data because they offer...
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To explore fresh strategies in colorectal cancer (CRC) chemotherapy, we evaluated the capability of the ruthenium-phloretin complex in exterminating colon cancer by effectively addressing multiple apoptotic mechanisms on HT-29 cancer cells together with an animal model of colorectal cancer activated by 1,2-dimethylhydrazine and dextran sulfate sodium. Our current approach offers tangible evidence of the application of the ruthenium-phloretin complex in future chemotherapy. The complex triggers intrinsic...
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This paper investigated the global synchronization of fractional-order memristive neural networks (FMNNs). To deal with the effect of reaction-diffusion and time delay, fractional partial and comparison theorem are introduced. Based on the set value mapping theory and Filippov solution, the activation function is extended to discontinuous case. Adaptive controllers with a compensator are designed owing to the existence of unknown parameters, with the help of Gronwall–Bellman inequality. Numerical...
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Considering the importance of reducing system operating costs and controlling pollutant emissions by optimizing the operation of the integrated energy system, the energy supply structure of the integrated energy system and the joint multiobjective optimization dispatching structure is analyzed in this paper based on a day-ahead economic optimization dispatching model of the integrated energy system. Afterwards, the multiobjective optimization model of the integrated energy system is studied and multiobjective...
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The majority of the Ethiopian population lives in rural areas and uses wood for domestic energy consumption. Using wood and fuel for domestic uses accounts for deforestation and health problems, which is also dangerous for the environment. The Ethiopian government has been planning to generate power from available renewable resources around the community. Therefore, determining the water surface potential of energy harvesting with floating solar photovoltaic system by using geographic information...
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Lipomas in fingers are rare and account for less than 1% of all cases. As a type of lipoma, the spindle cell lipoma is exceptional and it presents 1.5% of total adipocyte tumors. Moreover, its localization in the thumb is extremely rare. Only three cases have already been reported in adults; our case constitutes the fourth case, which is about a 61-year-old female who presented since 18 months a mass on the ulnar lateral aspect of the thumb. After clinical and radiological assessments, an entire...
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Many optimisation-based intrusion detection algorithms have been developed and are widely used for intrusion identification. This condition is attributed to the increasing number of audit data features and the decreasing performance of human-based smart intrusion detection systems regarding classification accuracy, false alarm rate, and classification time. Feature selection and classifier parameter tuning are important factors that affect the performance of any intrusion detection system. In this...
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The prediction of flow and heat transfer characteristics of liquid sodium with CFD technology is of significant importance for the design and safety analysis of sodium-cooled fast reactor. The accuracies and uncertainties of the CFD models should be evaluated to improve the confidence of the numerical results. In this work, the uncertainties from the turbulent model, boundary conditions, and physical properties for the flow and heat transfer of liquid sodium were evaluated against the experimental...
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Background. Variation in the prevalence of sarcopenia is related to the skeletal muscle index cutoff points applied. The objective of this pilot study was to examine the recruitment process for testing different sarcopenia definitions (ASMI cutoffs) in older Mexican adults. It explored whether the prevalence of sarcopenia decreased by applying ethnic- and gender-specific, DXA-derived appendicular skeletal muscle index (ASMI)-cutoff points in the definitions, as well as some associated factors in...
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The Benjamin–Ono equation is a useful model to describe the long internal gravity waves in deep stratified fluids. In this paper, the nonlocal Alice–Bob Benjamin–Ono system is induced via the parity and time-reversal symmetry reduction. By introducing an extended Bäcklund transformation, the symmetry-breaking soliton, breather, and lump solutions for this system are obtained through the derived Hirota bilinear form. By taking suitable constants in the involved ansatz functions, abundant fascinating...
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In this paper, we introduce the concept of -fuzzy semiprime ideal in a general poset. Characterizations of -fuzzy semiprime ideals in posets as well as characterizations of an -fuzzy semiprime ideal to be -fuzzy prime ideal are obtained. Also, -fuzzy prime ideals in a poset are characterized.
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Introduction. Tuberculosis is a major public health concern globally, especially in sub-Saharan African countries. It is the most common opportunistic infection and leading cause of mortality among people living with human immunodeficiency virus despite increased deliverance of antiretroviral therapy. Objectives. The aim of this study was to identify determinants of active tuberculosis among adult HIV positive patients after ART initiation in West Showa Zone public hospitals, Ethiopia. Methods. Multicentred...
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Introduction. Hypertension is a leading risk factor for cardiovascular mortality and an emerging public health concern in sub-Saharan Africa. Few studies have examined performance on the management of hypertension in this region, where the context may be distinct from other developing regions. Objectives. We aimed to determine the prevalence and correlates of hypertension, awareness, treatment, and control among adults in Botswana, a middle-income African country undergoing rapid demographic transition...
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Aim. This study aimed to compare the staining characteristics of a commercially available restorative glass ionomer cement to a formulation reinforced by the addition of carbon nanotubes and another formulation reinforced by the addition of silver nanoparticles to the powder of the same cement. Methodology. Twenty samples each of a control glass ionomer cement (PULPDENT® Glass Fill®, Pulpdent Corp. Watertown, MA, USA), control cement reinforced with 0.0006 gm (0.03% by weight) of carbon nanotubes...
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The accuracy of the counterweight positions in an automatic balancing system deeply affects dynamic balancing. Compensation vector is synthesized by the two counterweights located in the electromagnetic dual-weight automatic balancer. Therefore, if the position of the counterweight is inaccurate, it may result in a wrong adjustment and a larger imbalance of the rotor system. In this paper, an optimized pulse counting method for compensation vector calculation in an electromagnetic dual-weight balancing...
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Gynura bicolor (Roxb. and Willd.) DC (G. bicolor) is a dietary vegetable in the Far East. The aims of the present study were to investigate the antioxidant effects of the G. bicolor water extract (GBWE) and its ability to regulate the blood lipid and lipoprotein profiles. In this study, the pigment composition and antioxidant ability of the GBWE were analyzed. Syrian hamsters were fed a high-fat diet (HFD) and the GBWE for 12 weeks, and the blood lipid levels, lipoprotein profiles, and cholesterol...
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We investigate a stochastic SIRS model with transfer from infectious to susceptible and nonlinear incidence rate. First, using stochastic stability theory, we discuss stochastic asymptotic stability of disease-free equilibrium of this model. Moreover, if the transfer rate from infectious to susceptible is sufficiently large, disease goes extinct. Then, we obtain almost surely exponential stability of disease-free equilibrium, which implies that noises can lead to extinction of disease. By the Lyapunov...
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Abstract This study aimed to establish an extended morphometric dataset regarding the stapedius muscle for anatomists and otologists. The tympanic cavity of ten cadavers (five females, five males) aged with 75.70 ± 13.75 years was bilaterally dissected. Morphometric properties of the stapedius muscle (i.e., its muscular belly and tendon) and its relationship with the neighborhood structures including the facial nerve was evaluated. The length of the entire stapedius muscle was...
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Abstract Type 1 diabetes mellitus (T1DM) is a chronic metabolic disease caused by the destruction of pancreatic β-cells. Human dental pulp stem cells represent a promising source for cell-based therapies, owing to their easy, minimally invasive surgical access, and high proliferative capacity. It was reported that human dental pulp stem cells can differentiate into a pancreatic cell lineage in vitro; however, few studies have investigated their effects on diabetes. Our study aimed...
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New research highlights the risks of unrealistic optimism during the coronavirus pandemic -- Read more on ScientificAmerican.com
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Acne vulgaris (acne) is a common inflammatory disorder of the cutaneous pilo-sebaceous unit. Here we perform a genome-wide association analysis in the United Kingdom, comparing severe cases of acne (n=1,893) with controls (n=5,132). In a second stage, we genotype putative-associated loci in a further 2,063 acne cases and 1,970 controls. We identify three genome-wide significant associations: 11q13.1 (rs478304, Pcombined=3.23 × 10(-11), odds ratio (OR) = 1.20), 5q11.2 (rs38055, P(combined) = 4.58...
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Inflammation is thought to play a critical role in the pathogenesis of placentation disorders such as recurrent miscarriages, growth restriction, and preeclampsia. Recently, neutrophil extracellular traps (NETs) have emerged as a potential mechanism for promoting inflammation in both infectious and noninfectious disorders. To investigate a pathogenic role for NETs in placentation disorders, we studied a model of antiangiogenic factor-mediated pregnancy loss in wild-type (WT) mice and in mice deficient...
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Neutrophil extracellular trap (NET) formation represents a form of cell death distinct from apoptosis or necrosis, by which invading pathogens are simultaneously entangled and potentially eliminated. Increased NET formation is observed in systemic lupus erythematosus (SLE), rheumatoid arthritis, antineutrophil cytoplasmic antibody-associated small vessel vasculitis, antiphospholipid antibody syndrome (APS), and psoriasis. NETs contribute to the pathogenesis of autoimmunity by exposing cryptic autoepitopes,...
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Hepatitis C virus (HCV) is a major cause of chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a minority of patients can clear the virus spontaneously. Elimination of HCV during acute infection correlates with a rapid induction of innate, especially interferon (IFN)-induced genes, and a delayed induction of adaptive immune responses. There is a strong association between genetic variants in the IFNlambda (IL28B) locus with the rate of spontaneous clearance. Individuals...
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The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation
The liver is essential for the synthesis of plasma proteins and integration of lipid metabolism. While the role of transcriptional networks in these processes is increasingly understood, less is known about post-transcriptional control of gene expression by RNA-binding proteins (RBPs). Here, we show that the RBP vigilin is upregulated in livers of obese mice and in patients with fatty liver disease. By using in vivo, biochemical and genomic approaches, we demonstrate that vigilin controls very-low-density...
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