Surgical Infections, Ahead of Print.
Mon Jun 01, 2020 10:00
No abstract available
Fri May 29, 2020 03:00
No abstract available
Fri May 29, 2020 03:00
Background: The role of high-field 3-Tesla intraoperative magnetic resonance imaging (I-MRI) during awake craniotomy (AC) has not been extensively studied. We report the feasibility and safety of AC during 3-Tesla I-MRI. Methods: This retrospective descriptive report compared 3 groups: AC with minimal sedation and I-MRI; I-MRI-guided craniotomy under general anesthesia (GA), and; AC without I-MRI. Perioperative factors, surgical, anesthetic and radiologic complications, and postoperative...
Fri May 29, 2020 03:00
No abstract available
Fri May 29, 2020 03:00
Related ArticlesImpact of Formulary Restrictions on Antiepileptic Drug Dispensation Outcomes. Neurol Ther. 2020 May 30;: Authors: Mehta D, Davis M, Epstein AJ, Lee A Abstract INTRODUCTION: The aim of this analysis was to assess the relationship between formulary restrictions and antiepileptic drug (AED) dispensation in patients with focal seizure (FS). STUDY DESIGN: A retrospective cohort analysis was conducted using data from Symphony Health's...
Mon Jun 01, 2020 14:19
Related ArticlesHealthcare utilization and associated costs following initiation of perampanel in patients with epilepsy. Epilepsy Behav. 2020 May 28;110:107137 Authors: Morgan CL, Varga S, Tsong W, Jenkins-Jones S, Holden S Abstract PURPOSE: We compared health service utilization and costs for patients with epilepsy before and after initiation of perampanel and compared with matched controls. METHOD: Patients were selected from the Clinical...
Mon Jun 01, 2020 14:19
Condition: Gallbladder DiseasesInterventions: Procedure: Head on bed; Procedure: Head on pillowSponsor: Ajou University School of MedicineNot yet recruiting
Mon Jun 01, 2020 14:18
Conditions: Dysphagia, Esophageal; Dysphagia, Oral Phase; Dysphagia Comes and Goes; Thyroiditis; Thyroid Cancer; Thyroid Neoplasms; Thyroid Goiter; Thyroid Nodule (Benign)Intervention: Procedure: Total thyroidectomySponsor: Umraniye Education and Research HospitalRecruiting
Mon Jun 01, 2020 14:18
The rapamycin analogue everolimus (EVR) is a potent inhibitor of the mammalian target of rapamycin (mTOR) and clinically used to prevent allograft rejections as well as tumor growth. The pharmacokinetic and immunosuppressive efficacy of EVR have been extensively reported in patient populations and in vitro studies. However, dose‐dependent ex vivo effects upon acute EVR administration in healthy volunteers are rare. Moreover, immunosuppressive drugs are associated with neuroendocrine changes and...
Sun May 31, 2020 16:38
Abstract Since December 2019, a novel coronavirus (SARS‐CoV‐2) infection has been rapidly spreading worldwide and causing the respiratory illness, coronavirus disease 2019 (COVID‐19). The anti‐retroviral drug favipiravir (FPV) has been experimentally used for COVID‐19 treatment since March 2020 in Japan. However, the pharmacokinetics of FPV in critically ill patients is unknown. We measured the serum concentration of FPV using high‐performance liquid chromatography in patients with severe COVID‐19...
Sun May 31, 2020 15:29
Abstract In the last few months, an unprecedented number of laboratory tests for COVID‐19 have been developed at a remarkable speed. With the rapid adoption of these tests into clinical practice, combined with the widespread publicity they received, questions arose related to the different types of tests, their utility, performance, and regulatory approval status. The aim of this publication is to provide a general landscape of laboratory testing for COVID‐19 and offer a historical and regulatory...
Sun May 31, 2020 15:29
Background. Dental students are exposed to various infections and infective sources during their training, and on this aspect, their level of knowledge is suboptimal and practices are risky. Therefore, improving their knowledge and practices would contribute significantly to infection control. Objective. To ascertain the level of understanding of senior dental students regarding the infection control in the dental practice. Methods. A cross-sectional study was conducted among dental students (3rd...
Mon Jun 01, 2020 13:20
Background. This study investigated the potential therapeutic effects of acupoint catgut embedding (ACE) at ST36 and BL13 on lipopolysaccharide- (LPS-) induced acute respiratory distress syndrome (ARDS) in rats. Materials and Methods. Male Sprague-Dawley rats were randomized into the normal saline (NS group with a sham procedure), lipopolysaccharide (LPS group with a sham procedure), and LPS plus ACE (LPS+ACE with ACE at bilateral BL13 and ST36 acupoints one day before LPS injection) groups. After...
Mon Jun 01, 2020 12:50
Objective. Unstable pertrochanteric fractures are usually treated with internal fixation, and the integrity of the anteromedial cortex is an important factor for stability and healing. In this study, we described and analyzed the three-dimensional mapping technology and morphological characteristics of pertrochanteric fractures. Methods. Fifty-nine pertrochanteric fractures (OTA/AO 2007 types 31A2) were retrospectively reviewed. Computed tomographic (CT) images for all fractures were superimposed...
Mon Jun 01, 2020 12:50
Cartilage-bone interface (CBI) is a complex structure which bears important information in pathophysiology of osteoarthritis (OA). While high-frequency ultrasound (US) has been widely used for the investigation of articular cartilage, 3D imaging of CBI using US is less commonly reported in this field. Here, we adopted a 3D high-frequency ultrasound imaging approach specifically for the investigation of CBI in human knee samples. Fifteen osteochondral disks from the tibial plateau of seven OA patients...
Mon Jun 01, 2020 12:50
Celecoxib (CXB) is a COX-2-selective nonsteroidal anti-inflammatory drug used to control pain and various inflammatory conditions. CXB has limited oral bioavailability and a slow dissociation rate due to its poor water solubility. In order to enhance the oral bioavailability of CXB and reduce the frequency of administration, the present study was aimed at enhancing the aqueous solubility of CXB by a cosolvency technique and then at formulating and evaluating a CXB in situ floating gelling system...
Mon Jun 01, 2020 11:50
The aim of this study was to explore whether the long noncoding RNA nuclear paraspeckle assembly transcript 1 (NEAT1)/miR-34a/Snail1 and NEAT1/miR-204/Zeb1 pathways are involved in epithelial-mesenchymal transition (EMT) of lens epithelial cells (LECs). Primary human LECs (HLECs) were separated and cultured. Our results identified that TGF-β2 induces NEAT1 overexpression in a dose-dependent manner and a time-dependent manner. Additionally, TGF-β2 induced downregulation of E-cadherin and upregulation...
Mon Jun 01, 2020 11:50
Background. We report a modified transplantation surgical technique for CHD with dextrocardia which is rare and surgically challenging. Methods. From January 2015 to May 2018, 5 patients with end-stage CHD with dextrocardia underwent heart transplantation at our institute. They were 10, 29, 13, 15, and 22 years old, respectively; 3 of them had dextroversion, and the other 2 had mirror-image dextrocardia and post-TCPC. The atrial-atrial anastomosis was performed first between the donor’s upper-left...
Mon Jun 01, 2020 11:50
The objective of this study was to authenticate the ethnobotanical claims of the Nepeta ruderalis Buch.-Ham. (N. ruderalis) extract in the traditional system of medicine. Crude extract was prepared via a simple maceration process. DPPH free radical scavenging and carrageenan-induced rat paw edema models were used to monitor antioxidant and anti-inflammatory responses of the N. ruderalis extract. Furthermore, it was tested for antiplatelet aggregation, cardioprotective, and calcium channel antagonistic...
Mon Jun 01, 2020 11:50
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): K.B. Pandeya, Aditya Ganeshpurkar, Mahendra Kumar Mishra
Mon Jun 01, 2020 14:13
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): Niels Lynøe, Anders Eriksson
Mon Jun 01, 2020 14:13
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): Arturo Armone Caruso, Antonio Del Prete, Antonio Ivan Lazzarino
Mon Jun 01, 2020 14:13
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): Pierre DENIS
Mon Jun 01, 2020 14:13
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): Walter D. Cardona Maya, Alejandro Carvajal
Mon Jun 01, 2020 14:13
Publication date: Available online 1 June 2020Source: Medical HypothesesAuthor(s): Holly Pollard-Wright
Mon Jun 01, 2020 14:13
Publication date: Available online 31 May 2020Source: Medical HypothesesAuthor(s): Vittorio Pavoni, Lara Gianesello
Mon Jun 01, 2020 14:13
Publication date: Available online 31 May 2020Source: Medical HypothesesAuthor(s): Basic-Jukic Nikolina
Mon Jun 01, 2020 14:13
Publication date: Available online 30 May 2020Source: Medical HypothesesAuthor(s): Saleem Abdulrab, Sadeq Al-maweri, Esam Halboub
Mon Jun 01, 2020 14:13
Related ArticlesVirtual Spine: A novel, international teleconferencing program developed to increase the accessibility of spine education during the COVID-19 pandemic. World Neurosurg. 2020 May 28;: Authors: Rasouli JJ, Shin JH, Than KD, Gibbs WN, Baum GR, Baaj AA Abstract BACKGROUND: The coronavirus (COVID-19) pandemic effectively ended all major spine educational conferences in the first half of 2020. In response, the authors formed a "virtual" case-based...
Mon Jun 01, 2020 16:40
Related ArticlesVirtual Exploration of Safe Entry Zones in the Brainstem: Comprehensive Definition and Analysis of the Operative Approach. World Neurosurg. 2020 May 28;: Authors: Meybodi AT, Hendricks BK, Witten AJ, Hartman J, Tomlinson SB, Cohen-Gadol AA Abstract BACKGROUND: Detailed and accurate understanding of intrinsic brainstem anatomy and the inter-relationship between its internal tracts and nuclei and external landmarks is of paramount importance...
Mon Jun 01, 2020 16:40
Related ArticlesGiant intracranial extra-axial parietal-occipital cavernous hemangioma in an adolescent: case report. World Neurosurg. 2020 May 28;: Authors: Adamski A, Qian J, Adamo MA Abstract BACKGROUND: Extra-axial cavernous hemangiomas (EACH) are an extremely rare form of cerebral vascular malformations, occurring very infrequently in children and rarely exceeding 6.0cm in diameter (labeled as "giant"). Our case study highlights the radiographic,...
Mon Jun 01, 2020 16:40
Related ArticlesNeurosurgery Practice During Coronavirus Disease 2019 (COVID-19) Pandemic. World Neurosurg. 2020 May 28;: Authors: Ozoner B, Gungor A, Hasanov T, Toktas ZO, Kilic T Abstract Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a highly contagious, life-threatening condition with unprecedented impacts for worldwide societies and healthcare systems. Since the first detection in...
Mon Jun 01, 2020 16:40
Related ArticlesAneurysmal Subarachnoid Hemorrhage: Collateral Damage of COVID? World Neurosurg. 2020 May 28;: Authors: Bengzon Diestro JD, Li YM, Parra-Fariñas C, Sarma D, Bharatha A, Marotta TR, Spears J PMID: 32474100 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:40
Related ArticlesEndoscopic Endonasal Approach for Clival Chordoma with Subarachnoid Invasion: a 2D Step-by-Step Operative Video. World Neurosurg. 2020 May 28;: Authors: Albonette-Felicio T, Silveira-Bertazzo GS, Martínez-Pérez R, Shahein M, Zachariah M, Carrau RL, Prevedello DM Abstract Chordomas are slow-growing, low-grade, locally invasive and locally aggressive tumors. They peak at 40 - 60 years of age, with a male preponderance (2:1). Belonging to...
Mon Jun 01, 2020 16:40
Related ArticlesThe impact of newer generation anticonvulsant prophylaxis on seizure incidence after spontaneous intracerebral hemorrhage. World Neurosurg. 2020 May 28;: Authors: Christie C, Daggubati L, Patel N, Matthews N, Lehman E, Cockroft KM Abstract The role of prophylactic antiepileptic drugs (AEDs) in preventing seizures and/or improving outcome after intracerebral hemorrhage (ICH) remains controversial. Current guidelines recommend against prophylaxis....
Mon Jun 01, 2020 16:40
Related ArticlesCentral Nervous System Solitary Fibrous Tumor/Hemangiopericytoma Penetrating the Skull Bone: An Unusual Presentation. World Neurosurg. 2020 May 28;: Authors: Choi J, Kim J, Cho I, Shin J Abstract BACKGROUND: Central nervous system solitary fibrous tumor/hemangiopericytoma (CNS SFT/HPC) is a soft tissue neoplasm which accounts for less than 1% of all intracranial tumors. Its growth is mostly intracranial, usually along the sinuses. We...
Mon Jun 01, 2020 16:40
Related ArticlesComaneci-Assisted Coiling Embolization of a Post-Traumatic Carotid-Cavernous Fistula: Case Report. World Neurosurg. 2020 May 28;: Authors: Giorgianni A, Agosti E, Terrana A, Vinacci G, Nativo L, Valvassori L, Locatelli D, Lanzino G PMID: 32474096 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:40
Related ArticlesEffect of Shunting on Visual Outcomes and Headache in Patients with Idiopathic Intracranial Hypertension. World Neurosurg. 2020 May 28;: Authors: Daou BJ, Sweid A, Weinberg JH, Starke RM, Sergott RC, Doermann AS, Hauge J, Zanaty M, Chalouhi N, Gooch R, Herial N, Zarzour H, Jabbour P, Rosenwasser RH, Tjoumakaris S Abstract BACKGROUND: Visual dysfunction and headache are major symptoms in patients with idiopathic intracranial hypertension...
Mon Jun 01, 2020 16:40
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