Related ArticlesBracing for acute and subacute osteoporotic compression fractures: systematic review of the literature. World Neurosurg. 2020 May 28;: Authors: Hofler RC, Jones GA Abstract OBJECTIVE: Many treatment options for osteoporotic vertebral fractures are available, however, there exist limited and variable reports on efficacy of individual therapies. The objective of this study was to systematically review the literature for evidence of efficacy...
Mon Jun 01, 2020 16:40
Related ArticlesCOVID-19 and SARS-Cov-2 Infection: Pathophysiology and Clinical Effects on the Nervous System. World Neurosurg. 2020 May 28;: Authors: Abboud H, Abboud FZ, Kharbouch H, Arkha Y, Abbadi NE, Ouahabi AE Abstract Coronavirus disease 19 (COVID-19) is an infectious disease caused by SARS-Cov-2, resulting in severe acute respiratory syndrome, with high potential of spreading and infecting humans worldwide. Since January 2020, when the virus...
Mon Jun 01, 2020 16:40
Related ArticlesCOVID-19 associated encephalopathies and cerebrovascular disease: the New Orleans experience. World Neurosurg. 2020 May 28;: Authors: Scullen T, Keen J, Mathkour M, Dumont AS, Kahn L PMID: 32474092 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:40
Related ArticlesA moving Target? The Fate of LVOs Strokes pre-treated with IV-tPA in the Era of Mechanical Thrombectomy. World Neurosurg. 2020 May 28;: Authors: Rajah G, Saber H, Lieber B, Kappel A, Smitt M, Chamiraju P, Naryanan S, Luqman A Abstract BACKGROUND: Although still recommended, using IV-tPA for Large vessel occlusions (LVO) has been questioned in the era of mechanical thrombectomy (MT). We sought to determine the impact of IV-tPA if utilized...
Mon Jun 01, 2020 16:40
Related ArticlesChallenges to Neurosurgical Residency Training during COVID-19 Pandemic: An Indian Perspective. World Neurosurg. 2020 May 28;: Authors: Ruparelia J, Gosal JS, Garg M, Bhaskar S, Jha DK PMID: 32474090 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:40
Related ArticlesRisk factor for poor outcome of the elderly patients with aneurysmal subarachnoid hemorrhage based on the post hoc analysis of modified WFNS study. World Neurosurg. 2020 May 28;: Authors: Ozono I, Ikawa F, Hidaka T, Yoshiyama M, Matsuda S, Michihata N, Kobata H, Murayama Y, Sato A, Kato Y, Sano H, Yamaguchi S, Kurisu K Abstract OBJECTIVE: There is currently no precise guide for the treatment and management of elderly patients with aneurysmal...
Mon Jun 01, 2020 16:40
Related ArticlesRare Diffuse Intrinsic Pontine Glioma Metastasis Throughout the Brain and Spine. World Neurosurg. 2020 May 28;: Authors: Lu VM, Brown DA, Daniels DJ Abstract Diffuse intrinsic pontine glioma (DIPG) with H3 K27M mutation is a rare brain tumor that primarily affects children. It is extremely lethal, and our understanding of the natural course of this disease, and how it progresses, is lacking. We herein present a case that demonstrates...
Mon Jun 01, 2020 16:40
Abstract Objective We assessedthe etiology of idiopathic condylar resorptionby examining the effects of oestrogen and compressive mechanical stress under a low systemic oestrogen condition in temporomandibular joints (TMJ) caused by an ovariectomy. Materials and Methods Female rabbits were divided into non‐ovariectomy (non‐OVX) and ovariectomy (OVX) groups. A cortical osteotomy was performed witha custom device that wasincreased in length by 0.25 mm every 12 hoursfor 1 week after the operation,during...
Sun May 31, 2020 22:25
In reply to the letter to the editor "Tele(oral)medicine: A new approach during the COVID‐19 crisis"
Abstract We would like tocongratulate Villa et al fora recent published letter to the editor(Villa et al; 2020 ), emphasizing the use of tele(oral)medicine as an effective diagnostic tool(Estai et al , 2018),which could be usefulin the current time of crisis.The COVID‐19 pandemic, and the social isolation measures mandatedby health authorities haveled toa reassessing of the professional practicesin our Dental College.
Sun May 31, 2020 19:53
Abstract I used to begin my microbiology lecture series with a slogan “microbes rule the world”. And I continued by reminding the students that microbes, in fact, have been on earth billions of years before man and that they most probably stay here after mankind has been extinguished. The current SARS‐CoV‐2 pandemic makes this statement actual but also a bit creepy.
Sun May 31, 2020 19:53
Sun May 31, 2020 12:33
Abstract Coronaviridae is a family of single‐stranded positive enveloped RNA viruses. This article aimed to review the history of these viruses in the last 60 years since their discovery to understand what lessons can be learned from the past. A review of the PubMed database was carried out, describing taxonomy, classification, virology, genetic recombination, host adaptation, and main symptoms related to each type of virus. SARS‐CoV‐2 is responsible for the ongoing global pandemic, SARS‐CoV and...
Sun May 31, 2020 12:25
Abstract Gomes‐Filho published a systematic review and confirmed a strong association between periodontitis and pneumonia (Gomes‐Filho et al., 2020). Unlike the well‐established association between cardiovascular diseases and periodontitis as supported by more than 50 observational studies (cohort and case‐control studies) during the past 25 years (Stewart & West, 2016), fewer observational studies have been conducted to study the association between periodontitis and pneumonia as demonstrated...
Sun May 31, 2020 12:23
Abstract The outbreak of the novel corona virus had dramatic impact throughout the World. It was completely unexpected for most of us and we were not prepared at all to change our daily routines. When the first cases of deaths due to the novel corona virus were announced, the first reaction was an acute interest followed by some degree of ignorance and many people thought that the situation was being exaggerated. In a very short time, the novel corona virus became extremely popular in the media...
Sun May 31, 2020 12:19
Abstract For centuries it has been humankind's instinct to cover the mouth and nose when coughing or sneezing. Common sense would dictate this instinctively reduces the dispersion of aerosol and droplets and thus the spread of contact and airborne infections.
Sun May 31, 2020 22:04
Related ArticlesVibration pattern recognition using a compressed histogram of oriented gradients for snoring source analysis. Biomed Mater Eng. 2020 May 27;: Authors: Zhang Y, Zhao Z, Xu HJ, He C, Peng H, Gao Z, Xu ZY Abstract BACKGROUND: Snoring source analysis is essential for an appropriate surgical decision for both simple snorers and obstructive sleep apnea/hypopnea syndrome (OSAHS) patients. OBJECTIVE: As snoring sounds carry significant...
Mon Jun 01, 2020 18:00
Objective This study examined the severity of mobile phone addiction and its relationship with quality of life (QOL) in Chinese university students. Methods A total of 2,312 university students from Macao, Hong Kong and mainland China participated in this cross-sectional study. The Mobile Phone Addiction Scale (MPAS), and the World Health Organization Quality of Life-Brief version (WHOQOL-BREF) rating instruments were used to assess the severity of mobile phone addiction and QOL, respectively....
Mon Jun 01, 2020 03:00
Background To use competing analyses to estimate the prognostic value of KRAS mutation status in colorectal cancer (CRC) patients and to build nomogram for CRC patients who had KRAS testing. Method The cohort was selected from the Surveillance, Epidemiology, and End Results database. Cumulative incidence function model and multivariate Fine-Gray regression for proportional hazards modeling of the subdistribution hazard (SH) model were used to estimate the prognosis. An SH model based...
Mon Jun 01, 2020 03:00
Background In old field systems, the common woodlouse may have an indirect effect on a nursery web spider. Woodlice and nursery web spiders feed in different food chains, yet previous work demonstrated that the presence of woodlice is correlated with higher predation success by nursery web spiders upon their grasshopper prey. This finding suggested a new hypothesis which links two seemingly disparate food chains: when woodlice are present, the spider predator or the grasshopper prey...
Mon Jun 01, 2020 03:00
Background Depending on the stroke and distances of the events, swim starts have been estimated to account for 0.8% to 26.1% of the overall race time, with the latter representing the percentage in a 50 m sprint front crawl event (Cossor & Mason, 2001). However, it is still somewhat unclear what are the key physiological characteristics underpinning swim start performance. The primary aim of this study was to develop a multiple regression model to determine key lower body force-time...
Mon Jun 01, 2020 03:00
Cell culture provides useful model systems used in a wide range of biological applications, but its utility in marine invertebrates is limited due to the lack of immortalised cell lines. Primary cell and tissue cultures are typically used but remain poorly characterised for oysters, which can cause issues with experimental consistency and reproducibility. Improvements to methods of repeatable isolation, culture, and characterisation of oyster cells and tissues are required to help address these issues....
Mon Jun 01, 2020 03:00
The nation of Antigua and Barbuda has experienced major degradation of its coral reef ecosystems over the past 40+ years. The primary drivers of this degradation are multiple and are highly linked to anthropogenic influences, including over-exploitation and poor management of marine resources. The effectiveness of management actions in marine protected areas (MPAs) has often been hampered by a lack of data to inform management recommendations. This was emphasized by The Nature Conservancy’s (TNC)...
Mon Jun 01, 2020 03:00
Giant mustelids are a paraphyletic group of mustelids found in the Neogene of Eurasia, Africa and North America. Most are known largely from dental remains, with their postcranial skeleton mostly unknown. Here, we describe new craniodental and postcranial remains of the large lutrine Sivaonyx hendeyi and the leopard-size gulonine Plesiogulo aff. monspessulanus from the early Pliocene site Langebaanweg, South Africa. The new material of the endemic S. hendeyi, includes upper incisors and premolars,...
Mon Jun 01, 2020 03:00
Background Microsatellite loci, or single sequence repeats (SSR), are widely used as powerful markers in population genetics. They represent an attractive tool for studying plants such as grasses, whose evolution is driven by hybridisation and polyploidization. However, the development of microsatellite markers has been challenging and time-consuming, especially for non-model organisms lacking available genome-wide sequence data. One straightforward and low-cost approach is to transfer...
Mon Jun 01, 2020 03:00
Background Renal cell carcinoma (RCC) is a fatal disease, in which the PI3K/AKT/mTOR signaling pathway serves an important role in the tumorigenesis. Previous studies have reported the prognostic significance of PI3K/AKT/mTOR signaling pathway members in RCC; however, there is insufficient evidence to date to confirm this. Thus, the present study aimed to systematically investigate the prognostic roles of multiple PI3K/AKT/mTOR signaling proteins in clear cell RCC (ccRCC) using online...
Mon Jun 01, 2020 03:00
Background The efficacy and safety of 5α-reductase inhibitors (5ARIs) in treating prostate cancer (PCa) have not been fully determined. We performed a meta-analysis to evaluate the effectiveness and safety of 5ARIs for PCa patients. Methods A comprehensive literature search of online databases was conducted to obtain comparative studies exploring the effectiveness and safety of 5ARIs in treating PCa up to October 2019. Summarized odds ratio s (OR s) or hazard ratio s (HR s) were calculated...
Mon Jun 01, 2020 03:00
Related ArticlesLonger duration electroencephalogram arousals have a better relationship with impaired vigilance and health status in obstructive sleep apnoea. Sleep Breath. 2020 May 30;: Authors: Duce B, Kulkas A, Töyräs J, Terrill P, Hukins C Abstract PURPOSE: Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health consequences. Sleep fragmentation is a feature of OSA and is often determined by the arousal index (ArI),...
Mon Jun 01, 2020 16:34
Related ArticlesComorbid sleep apnea, post-traumatic stress disorder, and insomnia: underlying mechanisms and treatment implications-a commentary on El Solh et al.'s Impact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder. Sleep Breath. 2020 May 30;: Authors: Wallace DM, Sweetman A PMID: 32474830 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:34
Injectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model.
Related ArticlesInjectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model. Sleep Breath. 2020 May 30;: Authors: Moradi Tuchayi S, Tam J, Wojtkiewicz GR, Kawa NI, Javorsky E, Anderson RR, Garibyan L Abstract PURPOSE: Increased neck circumference is a major risk factor for obstructive sleep apnea (OSA). New data suggest that increased adipose tissue in the neck may be a contributory cause of OSA. The aim of this...
Mon Jun 01, 2020 16:34
Related ArticlesIn-depth surveillance of central sleep apnea in stable heart failure patients. Sleep Med. 2020 May 05;71:35-36 Authors: Ibrahim SH, Wharton R, Harmon E, Bonner H, Davis EM, Cho Y, Levy WC, Mazimba S, Kwon Y PMID: 32474404 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 16:34
Related ArticlesObstructive sleep apnea syndrome as a potential cause of nocturia in younger adults. Urology. 2020 May 28;: Authors: Miyauchi Y, Okazoe H, Tamaki M, Kakehi T, Ichikawa H, Arakawa Y, Mori Y, Koui F, Sugimoto M, Kakehi Y Abstract OBJECTIVES: To investigate the impact of age on the relationship between obstructive sleep apnea syndrome (OSAS), nocturia, and other lower urinary tract symptoms (LUTSs). METHODS: This was a secondary...
Mon Jun 01, 2020 16:34
Related ArticlesBiomarkers of Bone Turnover Identify Subsets of Chronic Kidney Disease Patients at Higher Risk for Fracture. J Clin Endocrinol Metab. 2020 May 31;: Authors: Hughes-Austin JM, Katz R, Semba RD, Kritchevsky S, Bauer DC, Sarnak MJ, Ginsberg C, Shlipak MG, Lima F, Malluche HH, Ix JH Abstract BACKGROUND: We sought to identify biomarkers that indicate low turnover on bone histomorphometry in CKD patients, and subsequently determined if this...
Mon Jun 01, 2020 17:53
Related Articles"Letter to the Editor: Distribution of Body Hair in Young Australian Women and Associations with Serum Androgen Concentrations". J Clin Endocrinol Metab. 2020 May 31;: Authors: Kiconco S, Teede HJ, Azziz R PMID: 32474600 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 17:53
Related ArticlesBrn3a/Pou4f1 functions as a tumor suppressor by targeting c-MET/STAT3 signaling in thyroid cancer. J Clin Endocrinol Metab. 2020 May 31;: Authors: Jung SN, Kang YE, Lee GH, Liu L, Oh C, Jin YL, Lim MA, Lee K, Oh T, Won HR, Chang JW, Koo BS Abstract BACKGROUND: Brn3a/Pou4f1 is a class IV POU domain-containing transcription factor and has been found to be expressed in a variety of cancers. However, the mechanism and action of Brn3a in thyroid...
Mon Jun 01, 2020 17:53
Related ArticlesPredicting mortality due to SARS-CoV-2: A mechanistic score relating obesity and diabetes to COVID-19 outcomes in Mexico. J Clin Endocrinol Metab. 2020 May 31;: Authors: Bello-Chavolla OY, Bahena-López JP, Antonio-Villa NE, Vargas-Vázquez A, González-Díaz A, Márquez-Salinas A, Fermín-Martínez CA, Naveja JJ, Aguilar-Salinas CA Abstract BACKGROUND: The SARS-CoV-2 outbreak poses challenge to healthcare systems due to high complication rates...
Mon Jun 01, 2020 17:53
Related ArticlesResponse to Letter to the Editor: Distribution of Body Hair in Young Australian Women and Associations with Serum Androgen Concentrations. J Clin Endocrinol Metab. 2020 May 31;: Authors: Skiba MA, Bell RJ, Islam RM, Karim MN, Davis SR PMID: 32474591 [PubMed - as supplied by publisher]
Mon Jun 01, 2020 17:53
Related ArticlesAntitumor effects of ivermectin at clinically feasible concentrations support its clinical development as a repositioned cancer drug. Cancer Chemother Pharmacol. 2020 May 30;: Authors: Juarez M, Schcolnik-Cabrera A, Dominguez-Gomez G, Chavez-Blanco A, Diaz-Chavez J, Duenas-Gonzalez A Abstract PURPOSE: Ivermectin is an antiparasitic drug that exhibits antitumor effects in preclinical studies, and as such is currently being repositioned...
Mon Jun 01, 2020 14:45
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