Αρχειοθήκη ιστολογίου

Αλέξανδρος Γ. Σφακιανάκης
ΩτοΡινοΛαρυγγολόγος
Αναπαύσεως 5
Άγιος Νικόλαος Κρήτη 72100
2841026182
6032607174

Δευτέρα 1 Ιουνίου 2020


Opening ASBMB publications freely to all [Editorial]
Molecular & Cellular Proteomics current issue
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Selection of Features with Consistent Profiles Improves Relative Protein Quantification in Mass Spectrometry Experiments [Research]
In bottom-up mass spectrometry-based proteomics, relative protein quantification is often achieved with data-dependent acquisition (DDA), data-independent acquisition (DIA), or selected reaction monitoring (SRM). These workflows quantify proteins by summarizing the abundances of all the spectral features of the protein (e.g. precursor ions, transitions or fragments) in a single value per protein per run. When abundances of some features are inconsistent with the overall protein profile (for technological...
Molecular & Cellular Proteomics current issue
17h
Characterization of Prenylated C-terminal Peptides Using a Thiopropyl-based Capture Technique and LC-MS/MS [Research]
Posttranslational modifications play a critical and diverse role in regulating cellular activities. Despite their fundamentally important role in cellular function, there has been no report to date of an effective generalized approach to the targeting, extraction, and characterization of the critical c-terminal regions of natively prenylated proteins. Various chemical modification and metabolic labeling strategies in cell culture have been reported. However, their applicability is limited to cell...
Molecular & Cellular Proteomics current issue
17h
Investigation of Inter- and Intratumoral Heterogeneity of Glioblastoma Using TOF-SIMS [Research]
Glioblastoma (GBM) is one of the most aggressive human cancers with a median survival of less than two years. A distinguishing pathological feature of GBM is a high degree of inter- and intratumoral heterogeneity. Intertumoral heterogeneity of GBM has been extensively investigated on genomic, methylomic, transcriptomic, proteomic and metabolomics levels, however only a few studies describe intratumoral heterogeneity because of the lack of methods allowing to analyze GBM samples with high spatial...
Molecular & Cellular Proteomics current issue
17h
Seminal Plasma Proteome as an Indicator of Sperm Dysfunction and Low Sperm Motility in Chickens [Research]
Molecular mechanisms underlying sperm motility have not been fully explained, particularly in chickens. The objective was to identify seminal plasma proteins associated with chicken sperm motility by comparing the seminal plasma proteomic profile of roosters with low sperm motility (LSM, n = 4) and high sperm motility (HSM, n = 4). Using a label-free MS-based method, a total of 522 seminal plasma proteins were identified, including 386 (~74%) previously reported and 136 novel ones. A total of 70...
Molecular & Cellular Proteomics current issue
17h
Characterization of Signaling Pathways Associated with Pancreatic {beta}-cell Adaptive Flexibility in Compensation of Obesity-linked Diabetes in db/db Mice [Research]
The onset of obesity-linked type 2 diabetes (T2D) is marked by an eventual failure in pancreatic β-cell function and mass that is no longer able to compensate for the inherent insulin resistance and increased metabolic load intrinsic to obesity. However, in a commonly used model of T2D, the db/db mouse, β-cells have an inbuilt adaptive flexibility enabling them to effectively adjust insulin production rates relative to the metabolic demand. Pancreatic β-cells from these animals have markedly reduced...
Molecular & Cellular Proteomics current issue
17h
MaxQuant Software for Ion Mobility Enhanced Shotgun Proteomics [Technological Innovation and Resources]
Ion mobility can add a dimension to LC-MS based shotgun proteomics which has the potential to boost proteome coverage, quantification accuracy and dynamic range. Required for this is suitable software that extracts the information contained in the four-dimensional (4D) data space spanned by m/z, retention time, ion mobility and signal intensity. Here we describe the ion mobility enhanced MaxQuant software, which utilizes the added data dimension. It offers an end to end computational workflow for...
Molecular & Cellular Proteomics current issue
17h
quality of care; +27 new citations
27 new pubmed citations were retrieved for your search. Click on the search hyperlink below to display the complete search results: quality of care These pubmed results were generated on 2020/06/01PubMed comprises more than millions of citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites.
pubmed: quality of care
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JPM, Vol. 10, Pages 47: Failure of Achieving Tacrolimus Target Blood Concentration Might Be Avoided by a Wide Genotyping of Transplanted Patients: Evidence from a Retrospective Study
JPM, Vol. 10, Pages 47: Failure of Achieving Tacrolimus Target Blood Concentration Might Be Avoided by a Wide Genotyping of Transplanted Patients: Evidence from a Retrospective Study Journal of Personalized Medicine doi: 10.3390/jpm10020047 Authors: Giovanni Pallio Natasha Irrera Alessandra Bitto Federica Mannino Letteria Minutoli Michelangelo Rottura Socrate Pallio Domenica Altavilla Angela Alibrandi Maria Concetta Marciano Maria Righi Carmen Mannucci Vincenzo...
Journal of Personalized Medicine
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How a US-UK trade agreement could affect NHS drug prices
The governments of the UK and US are working on the outlines of a trade agreement.1 Health has emerged as an early focus of public debate on the putative trade agreement, with many concerned that...
Latest headlines from BMJ
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Improved time to treatment failure and survival in ibrutinib-treated malignancies with a pharmaceutical care program: an observational cohort study
Abstract Ibrutinib treatment has been shown to increase survival in patients with B cell malignancies. Real-life data suggest a large part of discontinuations are due to toxicities, impairing ibrutinib efficacy. We aimed to assess the impact of a pharmaceutical care program on the efficacy and safety of ibrutinib. This single-center, cohort, observational study enrolled patients with B cell malignancies. Patients were either assigned to the program or to receive usual care, based...
Latest Results
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DNA damage and repair scenario in ameloblastoma.
Related ArticlesDNA damage and repair scenario in ameloblastoma. Oral Oncol. 2020 May 28;108:104804 Authors: Toprani SM Abstract Ameloblastoma is a rare human disease of benign neoplasm odontogenic tumor with a lower prevalence but higher recurrence rate. Etiology of ameloblastoma is not fully understood thus lacks implementation of curative treatments. One of the proposed models of evolution of ameloblastoma is related to alteration in DNA damage and...
pubmed: "oral oncol"[jour]
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Oral saliva and CVID-19.
Related ArticlesOral saliva and CVID-19. Oral Oncol. 2020 May 27;108:104821 Authors: Baghizadeh Fini M Abstract Outbreak pneumonia announced in Wuhan, China, in December 2019, had its causative factor classified as a new coronavirus (SARS-CoV-2). Since saliva can host several viruses including SARS-CoV-2, the transmission chance of viruses through saliva, particularly those causing respiratory infections, is unavoidable. COVID-19 can be detected through...
pubmed: "oral oncol"[jour]
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Mepitel Film is superior to Biafine cream in managing acute radiation-induced skin reactions in head and neck cancer patients: a randomised intra-patient controlled clinical trial.
Related ArticlesMepitel Film is superior to Biafine cream in managing acute radiation-induced skin reactions in head and neck cancer patients: a randomised intra-patient controlled clinical trial. J Med Radiat Sci. 2020 May 31;: Authors: Yan J, Yuan L, Wang J, Li S, Yao M, Wang K, Herst PM Abstract INTRODUCTION: We previously showed that Mepitel Film decreased the severity of acute radiation-induced skin reactions in head and neck cancer patients....
AA pubmed: head and neck
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Correspondence-Technical Note: Safe Nasoendoscopy Assisted Procedure in the Post COVID-19 Pandemic Era.
Related ArticlesCorrespondence-Technical Note: Safe Nasoendoscopy Assisted Procedure in the Post COVID-19 Pandemic Era. Clin Otolaryngol. 2020 May 31;: Authors: George A, Prince M, Coulson C Abstract For centuries it has been humankind's instinct to cover the mouth and nose when coughing or sneezing. Common sense would dictate this instinctively reduces the dispersion of aerosol and droplets and thus the spread of contact and airborne infections.PMID:...
AA pubmed: head and neck
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Periodontal disease and Helicobacter pylori infection in oral cavity: a meta-analysis of 2727 participants mainly based on Asian studies.
Related ArticlesPeriodontal disease and Helicobacter pylori infection in oral cavity: a meta-analysis of 2727 participants mainly based on Asian studies. Clin Oral Investig. 2020 May 30;: Authors: Liu Y, Li R, Xue X, Xu T, Luo Y, Dong Q, Liu J, Liu J, Pan Y, Zhang D Abstract OBJECTIVES: To assess the association between periodontal disease and Helicobacter pylori (H. pylori) infection in oral cavity. MATERIALS AND METHODS: We searched PubMed,...
AA pubmed: head and neck
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Complete decapitation by a self-constructed guillotine in a burned body - complex suicide or postmortem burning?
Related ArticlesComplete decapitation by a self-constructed guillotine in a burned body - complex suicide or postmortem burning? Int J Legal Med. 2020 May 30;: Authors: Ishigami A, Hata S, Ishida Y, Nosaka M, Kuninaka Y, Yamamoto H, Shimada E, Hashizume Y, Takayasu T, Kimura A, Furukawa F, Kondo T Abstract We report a suicide case of complete decapitation using a self-constructed guillotine. A 45-year-old man, whose body was severely burned, was...
AA pubmed: head and neck
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Brn3a/Pou4f1 functions as a tumor suppressor by targeting c-MET/STAT3 signaling in thyroid cancer.
Related ArticlesBrn3a/Pou4f1 functions as a tumor suppressor by targeting c-MET/STAT3 signaling in thyroid cancer. J Clin Endocrinol Metab. 2020 May 31;: Authors: Jung SN, Kang YE, Lee GH, Liu L, Oh C, Jin YL, Lim MA, Lee K, Oh T, Won HR, Chang JW, Koo BS Abstract BACKGROUND: Brn3a/Pou4f1 is a class IV POU domain-containing transcription factor and has been found to be expressed in a variety of cancers. However, the mechanism and action of Brn3a...
AA pubmed: head and neck
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Targeting EZH2 depletes LMP1-induced activated regulatory T cells enhancing antitumor immunity in nasopharyngeal carcinoma.
Related ArticlesTargeting EZH2 depletes LMP1-induced activated regulatory T cells enhancing antitumor immunity in nasopharyngeal carcinoma. J Cancer Res Ther. 2020;16(2):309-319 Authors: Sun W, Chen L, Tang J, Zhang C, Wen Y, Wen W Abstract Objective: Regulatory T cells (Tregs) are critical factors that impair antitumor immunity. Epstein-Barr virus (EBV)-encoded latent membrane protein 1 (LMP1) is one of the most pathogenic factors in nasopharyngeal...
AA pubmed: head and neck
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Limitations of ultrasound in predicting bilaterality vs unilaterality of well-differentiated carcinoma of the thyroid.
Related ArticlesLimitations of ultrasound in predicting bilaterality vs unilaterality of well-differentiated carcinoma of the thyroid. Am J Otolaryngol. 2020 May 08;41(4):102543 Authors: Bahat Dinur A, Quint E, Lupo L, Fraenkel M, El-Saied S, Joshua BZ Abstract PURPOSE: The purpose of this study is to assess the efficacy of ultrasonography in the differentiation of a bilateral and a unilateral WDTC to help physicians decide on performing a total...
AA pubmed: head and neck
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Surgical results of infected preauricular sinus: No need for delay.
Related ArticlesSurgical results of infected preauricular sinus: No need for delay. Int J Pediatr Otorhinolaryngol. 2020 May 21;135:110129 Authors: Han JS, Park JM, Han JJ, Cho YS, Vidal JL, Park SY, Park SN Abstract OBJECTIVES: This study was performed to propose the proper surgical timing of infected preauricular sinus (PAS) by comparing surgical results of active infection PAS group (AIPASG) to infection-controlled/or non-infected PAS group (IC/NIPASG)....
AA pubmed: head and neck
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Chronic rhinosinusitis linked to high microbiome dissimilarity among different patients and within individuals over time.
Related ArticlesChronic rhinosinusitis linked to high microbiome dissimilarity among different patients and within individuals over time. Ann Allergy Asthma Immunol. 2020 May 28;: Authors: Foster KJ, Naqib A, Schleimer RP, Batra PS, Mahdavinia M PMID: 32474157 [PubMed - as supplied by publisher]
AA pubmed: head and neck
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Endoscopic Endonasal Approach for Clival Chordoma with Subarachnoid Invasion: a 2D Step-by-Step Operative Video.
Related ArticlesEndoscopic Endonasal Approach for Clival Chordoma with Subarachnoid Invasion: a 2D Step-by-Step Operative Video. World Neurosurg. 2020 May 28;: Authors: Albonette-Felicio T, Silveira-Bertazzo GS, Martínez-Pérez R, Shahein M, Zachariah M, Carrau RL, Prevedello DM Abstract Chordomas are slow-growing, low-grade, locally invasive and locally aggressive tumors. They peak at 40 - 60 years of age, with a male preponderance (2:1). Belonging...
AA pubmed: head and neck
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Comaneci-Assisted Coiling Embolization of a Post-Traumatic Carotid-Cavernous Fistula: Case Report.
Related ArticlesComaneci-Assisted Coiling Embolization of a Post-Traumatic Carotid-Cavernous Fistula: Case Report. World Neurosurg. 2020 May 28;: Authors: Giorgianni A, Agosti E, Terrana A, Vinacci G, Nativo L, Valvassori L, Locatelli D, Lanzino G PMID: 32474096 [PubMed - as supplied by publisher]
AA pubmed: head and neck
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A moving Target? The Fate of LVOs Strokes pre-treated with IV-tPA in the Era of Mechanical Thrombectomy.
Related ArticlesA moving Target? The Fate of LVOs Strokes pre-treated with IV-tPA in the Era of Mechanical Thrombectomy. World Neurosurg. 2020 May 28;: Authors: Rajah G, Saber H, Lieber B, Kappel A, Smitt M, Chamiraju P, Naryanan S, Luqman A Abstract BACKGROUND: Although still recommended, using IV-tPA for Large vessel occlusions (LVO) has been questioned in the era of mechanical thrombectomy (MT). We sought to determine the impact of IV-tPA if utilized...
AA pubmed: head and neck
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Implant-supported oral rehabilitation in oncology patients: a retrospective cohort study.
Related ArticlesImplant-supported oral rehabilitation in oncology patients: a retrospective cohort study. Br J Oral Maxillofac Surg. 2020 May 27;: Authors: Patel J, Antov H, Nixon P Abstract Oral rehabilitation after treatment for head and neck cancer can be challenging. Implant-supported rehabilitation can considerably improve oral health-related quality of life, but there is a dearth of contemporary evidence of reported outcomes and trends in this...
AA pubmed: head and neck
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Impact of metformin on immunological markers: Implication in its anti-tumor mechanism.
Related ArticlesImpact of metformin on immunological markers: Implication in its anti-tumor mechanism. Pharmacol Ther. 2020 May 28;:107585 Authors: Chen GG, Woo PYM, Ng SCP, Wong GKC, Chan DTM, van Hasselt CA, Tong MCF, Poon WS Abstract Metformin, an anti-hyperglycemic drug, has been known to have antitumor properties for around 15 years. Although there are a number of reports attributing the antitumor function of metformin to its impact on energy...
AA pubmed: head and neck
17h
Japanese guidelines for allergic rhinitis 2020.
Related ArticlesJapanese guidelines for allergic rhinitis 2020. Allergol Int. 2020 May 27;: Authors: Okubo K, Kurono Y, Ichimura K, Enomoto T, Okamoto Y, Kawauchi H, Suzaki H, Fujieda S, Masuyama K, Japanese Society of Allergology Abstract Like asthma and atopic dermatitis, allergic rhinitis is an allergic disease, but of the three, it is the only type I allergic disease. Allergic rhinitis includes pollinosis, which is intractable and reduces quality...
AA pubmed: head and neck
17h
Prognostic capacity of the lymph node ratio in squamous cell carcinomas of the head and neck.
Related ArticlesPrognostic capacity of the lymph node ratio in squamous cell carcinomas of the head and neck. Acta Otorrinolaringol Esp. 2020 May 27;: Authors: León X, Neumann E, Gutierrez A, García J, Quer M, López M Abstract INTRODUCTION AND OBJECTIVES: Lymph node density or lymph node ratio (LNR), defined as the quotient between the total number of positive lymph nodes and the total number of dissected lymph nodes, has demonstrated a prognostic...
AA pubmed: head and neck
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Carbon monoxide controls microglial erythrophagocytosis by regulating CD36 surface expression to reduce the severity of hemorrhagic injury
Main points Carbon monoxide produced by heme oxygenase controls microglial erythrophagocytosis via a pathway involving CD36 surface‐expression. CD36‐deficiency leads to aggravated neuronal injury following experimental subarachnoid hemorrhage in mice. Abstract Microglial erythrophagocytosis is crucial in injury response to hemorrhagic stroke. We hypothesized that regulation of microglial erythrophagocytosis via HO‐1/CO depends on a pathway involving reactive oxygen species (ROS) and...
Glia
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Melatonin In Acute Mania Investigation (MIAMI-UK). A randomised controlled trial of add-on melatonin in bipolar disorder.
Related ArticlesMelatonin In Acute Mania Investigation (MIAMI-UK). A randomised controlled trial of add-on melatonin in bipolar disorder. Bipolar Disord. 2020 May 31;: Authors: Quested DJ, Gibson JC, Sharpley AL, Cordey JH, Economou A, De Crescenzo F, Voysey M, Lawson J, Rendell JM, Al-Taiar H, Lennox A, Ahmad F, Geddes JR Abstract OBJECTIVES: Current options for treating emergent episodes of hypomania and mania in bipolar disorder are limited. Our objective...
pubmed: sleep
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Sweet Daniel James.
Related ArticlesSweet Daniel James. Acad Emerg Med. 2020 May 31;: Authors: O'Connor L Abstract In the weeks of the pandemic, I find peace in the ritual of rocking my son to sleep every night. We have our routine: fleecy pajamas and our sturdy white rocking chair. I sing Sweet Baby James1 , the James Taylor classic, once, sometimes twice, always sure to change the chorus to "Sweet Daniel James". He falls asleep cradled against me, mouth open, milky breath...
pubmed: sleep
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Editorial Perspective: Perils and promise for child and adolescent sleep and associated psychopathology during the COVID-19 pandemic.
Related ArticlesEditorial Perspective: Perils and promise for child and adolescent sleep and associated psychopathology during the COVID-19 pandemic. J Child Psychol Psychiatry. 2020 May 31;: Authors: Becker SP, Gregory AM Abstract It is anticipated that the novel coronavirus disease 2019 (COVID-19) pandemic and associated societal response will have wide-ranging impacts on youth development and mental health. Sleep is crucial for child and adolescent...
pubmed: sleep
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Longer duration electroencephalogram arousals have a better relationship with impaired vigilance and health status in obstructive sleep apnoea.
Related ArticlesLonger duration electroencephalogram arousals have a better relationship with impaired vigilance and health status in obstructive sleep apnoea. Sleep Breath. 2020 May 30;: Authors: Duce B, Kulkas A, Töyräs J, Terrill P, Hukins C Abstract PURPOSE: Obstructive sleep apnoea (OSA) is a prevalent sleep disorder with significant health consequences. Sleep fragmentation is a feature of OSA and is often determined by the arousal index (ArI),...
pubmed: sleep
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Comorbid sleep apnea, post-traumatic stress disorder, and insomnia: underlying mechanisms and treatment implications-a commentary on El Solh et al.'s Impact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder.
Related ArticlesComorbid sleep apnea, post-traumatic stress disorder, and insomnia: underlying mechanisms and treatment implications-a commentary on El Solh et al.'s Impact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder. Sleep Breath. 2020 May 30;: Authors: Wallace DM, Sweetman A PMID: 32474830 [PubMed - as supplied by publisher]
pubmed: sleep
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Injectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model.
Related ArticlesInjectable slurry for selective destruction of neck adipose tissue in New Zealand obese mouse model. Sleep Breath. 2020 May 30;: Authors: Moradi Tuchayi S, Tam J, Wojtkiewicz GR, Kawa NI, Javorsky E, Anderson RR, Garibyan L Abstract PURPOSE: Increased neck circumference is a major risk factor for obstructive sleep apnea (OSA). New data suggest that increased adipose tissue in the neck may be a contributory cause of OSA. The aim of this...
pubmed: sleep
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Homeostatic state of microglia in a rat model of chronic sleep restriction.
Related ArticlesHomeostatic state of microglia in a rat model of chronic sleep restriction. Sleep. 2020 May 31;: Authors: Hall S, Deurveilher S, Robertson GS, Semba K Abstract Chronic sleep restriction (CSR) negatively impacts brain functions. Whether microglia, the brain's resident immune cells, play any role is unknown. We studied microglia responses to CSR using a rat model featuring slowly rotating wheels (3 h on/1 h off), which was previously shown...
pubmed: sleep
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Passion for an activity: A new predictor of sleep quality.
Related ArticlesPassion for an activity: A new predictor of sleep quality. Sleep. 2020 May 31;: Authors: Bélanger JJ, Raafat KA, Nisa CF, Schumpe BM Abstract STUDY OBJECTIVES: The present research examines the relationship between people's frequent involvement in an activity they like and find important (i.e., a passion) and the quality of their sleep. Research on the dualistic model of passion1-2 has widely documented the relationship between individual's...
pubmed: sleep
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A cluster of SARS-CoV-2 infection among Italian tourists visiting India, March 2020.
Related ArticlesA cluster of SARS-CoV-2 infection among Italian tourists visiting India, March 2020. Indian J Med Res. 2020 May 30;: Authors: Vivian Thangaraj JW, Murhekar M, Mehta Y, Kataria S, Brijwal M, Gupta N, Choudhary A, Malhotra B, Vyas M, Sharma H, Yadav N, Bhatnagar T, Gupta N, Dar L, Gangakhedkar RR, Bhargava B Abstract Background & objectives: A cluster of SARS-CoV-2 infection occurred among Italian tourists visiting India. We report...
pubmed: sleep
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Vibration pattern recognition using a compressed histogram of oriented gradients for snoring source analysis.
Related ArticlesVibration pattern recognition using a compressed histogram of oriented gradients for snoring source analysis. Biomed Mater Eng. 2020 May 27;: Authors: Zhang Y, Zhao Z, Xu HJ, He C, Peng H, Gao Z, Xu ZY Abstract BACKGROUND: Snoring source analysis is essential for an appropriate surgical decision for both simple snorers and obstructive sleep apnea/hypopnea syndrome (OSAHS) patients. OBJECTIVE: As snoring sounds carry significant...
pubmed: sleep
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Command application of UK military climatic guidance on Exercise SAIF SAREEA 3.
Related ArticlesCommand application of UK military climatic guidance on Exercise SAIF SAREEA 3. BMJ Mil Health. 2020 May 30;: Authors: Smith MB, White S Abstract Health and risk management of personnel in hot climates remains a Commander's responsibility, with Joint Service Publication 539 Heat Illness and Cold Injury: Prevention and Management (JSP 539) being the guiding document for the UK military. This policy can be challenging to interpret occasionally,...
pubmed: sleep
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Dopamine brain single-photon emission computed tomography (SPECT) imaging helps to determine the alternative effect of dopamine agonist in treating patients with rapid eye movement sleep behavior disorder (RBD).
Related ArticlesDopamine brain single-photon emission computed tomography (SPECT) imaging helps to determine the alternative effect of dopamine agonist in treating patients with rapid eye movement sleep behavior disorder (RBD). Sleep Med. 2020 May 07;71:37-38 Authors: Chang A, Lai YH, Chang A, Wang HC, Guilleminault C, Lin CM PMID: 32474405 [PubMed - as supplied by publisher]
pubmed: sleep
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In-depth surveillance of central sleep apnea in stable heart failure patients.
Related ArticlesIn-depth surveillance of central sleep apnea in stable heart failure patients. Sleep Med. 2020 May 05;71:35-36 Authors: Ibrahim SH, Wharton R, Harmon E, Bonner H, Davis EM, Cho Y, Levy WC, Mazimba S, Kwon Y PMID: 32474404 [PubMed - as supplied by publisher]
pubmed: sleep
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Prenatal particulate air pollution and newborn telomere length: Effect modification by maternal antioxidant intakes and infant sex.
Related ArticlesPrenatal particulate air pollution and newborn telomere length: Effect modification by maternal antioxidant intakes and infant sex. Environ Res. 2020 May 21;187:109707 Authors: Lee AG, Cowell W, Kannan S, Ganguri HB, Nentin F, Wilson A, Coull BA, Wright RO, Baccarelli A, Bollati V, Wright RJ Abstract BACKGROUND: Evidence links gestational exposure to particulate matter with an aerodynamic diameter of less than 2.5 μm (PM2.5) with changes...
pubmed: sleep
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Course and impact of sleep disturbance in newly diagnosed epilepsy: A prospective registry study.
Related ArticlesCourse and impact of sleep disturbance in newly diagnosed epilepsy: A prospective registry study. Clin Neurol Neurosurg. 2020 May 25;195:105963 Authors: Xu Y, Hackett ML, Nikpour A, Somerville E, Bleasel A, Ireland C, Ghougassian DF, Anderson CS, Glozier N Abstract OBJECTIVE: To determine the course of sleep distrurbance (insomnia symptoms and short sleep duration) after a diagnosis of epilepsy and their associations with seizure control,...
pubmed: sleep
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Relationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndrome.
Related ArticlesRelationship between parent-reported gastrointestinal symptoms, sleep problems, autism spectrum disorder symptoms, and behavior problems in children and adolescents with 22q11.2 deletion syndrome. Res Dev Disabil. 2020 May 28;104:103698 Authors: Leader G, Murray M, O'Súilleabháin PS, Maher L, Naughton K, Arndt S, White K, Traina I, Mannion A Abstract BACKGROUND: 22q11.2 deletion syndrome (22q) is a chromosome disorder, where a segment...
pubmed: sleep
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A Butterfly Flaps its Wings: Extinction of Biological Experience and the Origins of Allergy.
Related ArticlesA Butterfly Flaps its Wings: Extinction of Biological Experience and the Origins of Allergy. Ann Allergy Asthma Immunol. 2020 May 28;: Authors: Prescott SL Abstract OBJECTIVE: The grand global challenges of the Anthropocene are interdependent with ample evidence that reduced early-life 'experience' of biodiversity primes for immune dysregulation and a higher propensity low-grade inflammation, increasing the risk of allergy many other...
pubmed: sleep
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Reply to Carvalho.
Related ArticlesReply to Carvalho. J Allergy Clin Immunol Pract. 2020 May 28;: Authors: Nyenhuis SM, Greiwe J, Zeiger JS, Nanda A, Cooke A PMID: 32474131 [PubMed - as supplied by publisher]
pubmed: sleep
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Do no harm: reaffirming the value of evidence and equipoise while minimizing cognitive bias in the COVID-19 era.
Related ArticlesDo no harm: reaffirming the value of evidence and equipoise while minimizing cognitive bias in the COVID-19 era. Chest. 2020 May 28;: Authors: Ramnath VR, McSharry DG, Malhotra A PMID: 32473949 [PubMed - as supplied by publisher]
pubmed: sleep
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Going gentle into that pathogen-induced goodnight.
Related ArticlesGoing gentle into that pathogen-induced goodnight. J Invertebr Pathol. 2020 May 28;:107398 Authors: Lovett B, St Leger RJ, de Fine Licht HH Abstract A diverse set of pathogens have evolved extended phenotypes that manipulate the moribund behavior of their various insect hosts. By elevating host positioning at death, a phenomenon called "summit disease", these pathogens have been shown to have higher fitness. Though a few summit disease...
pubmed: sleep
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Obstructive sleep apnea syndrome as a potential cause of nocturia in younger adults.
Related ArticlesObstructive sleep apnea syndrome as a potential cause of nocturia in younger adults. Urology. 2020 May 28;: Authors: Miyauchi Y, Okazoe H, Tamaki M, Kakehi T, Ichikawa H, Arakawa Y, Mori Y, Koui F, Sugimoto M, Kakehi Y Abstract OBJECTIVES: To investigate the impact of age on the relationship between obstructive sleep apnea syndrome (OSAS), nocturia, and other lower urinary tract symptoms (LUTSs). METHODS: This was a secondary...
pubmed: sleep
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[Beliefs and perceptions of the diagnosis and treatment of fibromyalgia in a group of rehabilitation and physical medicine specialists in Colombia].
Related Articles[Beliefs and perceptions of the diagnosis and treatment of fibromyalgia in a group of rehabilitation and physical medicine specialists in Colombia]. Rehabilitacion (Madr). 2020 May 27;: Authors: Fernández-Avila DG, Rincón Riaño DN, Ronderos DM, Gutiérrez JM Abstract INTRODUCTION: Fibromyalgia is a chronic disease characterised by the presence of musculoskeletal pain, usually associated with other symptoms, including depression, fatigue,...
pubmed: sleep
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Population-specific profiling of <em>CCL3L1</em> copy number of the three major ethnic groups in Malaysia and the implication on HIV susceptibility
Publication date: Available online 1 June 2020Source: GeneAuthor(s): Irma Izani Mohamad Isa, Jalilah Jamaluddin, Nurfarahin Hanini Achim, Suhaili Abubakar
Gene
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How can I make the most of working from home?
Working differently can bring opportunitiesCharlotte Squires, ST3 medical registrar, Borders General Hospital“Remote working has been something of an eye opener. Clinically, a challenge has been...
Latest headlines from BMJ
18h
Cosmetics, Vol. 7, Pages 40: Broussonetia papyrifera Promotes Hair Growth Through the Regulation of β-Catenin and STAT6 Target Proteins: A Phototrichogram Analysis of Clinical Samples
Cosmetics, Vol. 7, Pages 40: Broussonetia papyrifera Promotes Hair Growth Through the Regulation of β-Catenin and STAT6 Target Proteins: A Phototrichogram Analysis of Clinical Samples Cosmetics doi: 10.3390/cosmetics7020040 Authors: Young Han Lee Gaewon Nam Myong-Ki Kim Seok-Cheol Cho Bu Young Choi Broussonetia papyrifera (B.papyrifera), belonging to the Moraceae family, is known to elicit anti-inflammatory, antioxidant, anti-tyrosinase, anticancer, antinociceptive,...
Cosmetics
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The Weight Optimization Revamping Lifestyle using the Dietary Guidelines (WORLD) Study: Sustained Weight Loss Over 12 Months.
Related ArticlesThe Weight Optimization Revamping Lifestyle using the Dietary Guidelines (WORLD) Study: Sustained Weight Loss Over 12 Months. Obesity (Silver Spring). 2020 May 31;: Authors: Psota TL, Tindall AM, Lohse B, Miller PE, Petersen KS, Kris-Etherton PM Abstract OBJECTIVE: This study aimed to compare two energy-restricted, nutrient-dense diets at the upper or lower ends of the dietary fat recommendation range (lower fat [20% energy from fat]...
pubmed: health technology
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Punicalagin Activates AMPK/PGC-1α/Nrf2 Cascade in Mice: The Potential Protective Effect Against Prenatal Stress.
Related ArticlesPunicalagin Activates AMPK/PGC-1α/Nrf2 Cascade in Mice: The Potential Protective Effect Against Prenatal Stress. Mol Nutr Food Res. 2020 May 30;:e2000312 Authors: Cao K, Lv W, Hu S, Gao J, Liu J, Feng Z Abstract SCOPE: Prenatal stress is closely associated with poor health outcomes for offspring, yet the specific mechanisms and effective interventions remain limited. METHODS AND RESULTS: In the present study, both male and female...
pubmed: health technology
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Chemical And Mechanical Characterization Of Hyaluronic Acid Hydrogel Cross-Linked With Polyethylen Glycol And Its Use In Dermatology.
Related ArticlesChemical And Mechanical Characterization Of Hyaluronic Acid Hydrogel Cross-Linked With Polyethylen Glycol And Its Use In Dermatology. Dermatol Ther. 2020 May 31;:e13747 Authors: Zerbinati N, Esposito C, Cipolla G, Calligaro A, Monticelli D, Martina V, Golubovic M, Binic I, Sigova J, Gallo AL, D'Este E, Jafferany M, Pratosoni M, Tirant M, Van Thuong N, Sangalli F, Rauso R, Lotti T Abstract INTRODUCTION: Hydrogels based on hyaluronic acid...
pubmed: health technology
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Cross-scanning optical coherence tomography angiography for eye motion correction.
Related ArticlesCross-scanning optical coherence tomography angiography for eye motion correction. J Biophotonics. 2020 May 31;: Authors: Kim HJ, Song BJ, Choi Y, Kim BM Abstract We propose a cross-scanning optical coherence tomography (CS-OCT) system to correct eye motion artifacts in OCT angiography images. This system employs a dual illumination configuration with two orthogonally polarized beams, each of which simultaneously perform raster scanning...
pubmed: health technology
18h
Imaging the Invisible - Bioorthogonal Raman Probes for Imaging of Cells and Tissues.
Related ArticlesImaging the Invisible - Bioorthogonal Raman Probes for Imaging of Cells and Tissues. J Biophotonics. 2020 May 31;:e202000129 Authors: Azemtsop Matanfack G, Rüger J, Stiebing C, Schmitt M, Popp J Abstract A revolutionary avenue for vibrational imaging with super-multiplexing capability can be seen in the recent development of Raman-active bioortogonal tags or labels. These tags and isotopic labels represent groups of chemically inert and...
pubmed: health technology
18h
A four-long noncoding RNA signature predicts survival of hepatocellular carcinoma patients.
Related ArticlesA four-long noncoding RNA signature predicts survival of hepatocellular carcinoma patients. J Clin Lab Anal. 2020 May 30;:e23377 Authors: Jiang H, Zhao L, Chen Y, Sun L Abstract BACKGROUND: Hepatocellular carcinoma (HCC) is a common neoplasm located in the liver. Accumulating evidence has highlighted that long noncoding RNAs (lncRNAs) are correlated with the survival of HCC patients. This study focuses on finding a lncRNA signature to...
pubmed: health technology
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Notch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis.
Related ArticlesNotch signaling regulates Akap12 expression and primary cilia length during renal tubule morphogenesis. FASEB J. 2020 May 31;: Authors: Mukherjee M, Ratnayake I, Janga M, Fogarty E, Scheidt S, Grassmeyer J, deRiso J, Chandrasekar I, Ahrenkiel P, Kopan R, Surendran K Abstract Alagille syndrome patients present with loss of function mutations in either JAG1 or NOTCH2. About 40%-50% of patients have kidney abnormalities, and frequently display...
pubmed: health technology
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Mental Health Status of Dermatologists during the COVID-19 Pandemic; A Technology-based Therapy.
Related ArticlesMental Health Status of Dermatologists during the COVID-19 Pandemic; A Technology-based Therapy. Dermatol Ther. 2020 May 31;:e13723 Authors: Goldust M, Agarwal K, Kroumpouzos G, Jafferany M, Lotti T, Podder I PMID: 32474959 [PubMed - as supplied by publisher]
pubmed: health technology
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Towards sustainable environmental quality: Priority research questions for Asia.
Related ArticlesTowards sustainable environmental quality: Priority research questions for Asia. Environ Toxicol Chem. 2020 May 30;: Authors: Leung KMY, Yeung KWY, You J, Choi K, Zhang X, Smith R, Zhou GJ, Yung MMN, Arias-Barreiro C, An YJ, Burket SR, Dwyer R, Goodkin N, Hii YS, Hoang T, Humphrey C, Iwai CB, Jeong SW, Juhel G, Karami A, Kyriazi-Huber K, Lee KC, Lin BL, Lu B, Martin P, Nillos MG, Oginawati K, Rathnayake IVN, Risjani Y, Shoeb M, Tan CH, Tsuchiya MC, Ankley...
pubmed: health technology
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Improvement in mechanical properties and biodegradability of PLA using poly(ethylene glycol) and triacetin for antibacterial wound dressing applications.
Related ArticlesImprovement in mechanical properties and biodegradability of PLA using poly(ethylene glycol) and triacetin for antibacterial wound dressing applications. Prog Biomater. 2020 May 30;: Authors: Darabian B, Bagheri H, Mohammadi S Abstract Wound is among the most common injuries. A suitable wound dressing has a significant effect on the healing process. In this study, a porous wound dressing was prepared using poly (lactic acid) (PLA) and...
pubmed: health technology
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Enrichment and Characterization of Human and Murine Pulmonary Mesenchymal Progenitor Cells (MPC ).
Related ArticlesEnrichment and Characterization of Human and Murine Pulmonary Mesenchymal Progenitor Cells (MPC ). Methods Mol Biol. 2020;2155:125-140 Authors: Summers M, Helm K, Majka SM Abstract Tissue resident mesenchymal progenitor cells (MPC) are important regulators of tissue repair or regeneration, remodeling, inflammation, and angiogenesis. Here we describe a technology used to define, isolate, and characterize a population of resident lung MPC...
pubmed: health technology
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Potential of Arbidol for Post-exposure Prophylaxis of COVID-19 Transmission-A Preliminary Report of a Retrospective Cohort Study.
Related ArticlesPotential of Arbidol for Post-exposure Prophylaxis of COVID-19 Transmission-A Preliminary Report of a Retrospective Cohort Study. Curr Med Sci. 2020 May 30;: Authors: Zhang JN, Wang WJ, Peng B, Peng W, Zhang YS, Wang YL, Wan Y, Chang J, Mao L, Miao XP, Li YN, Zhou YF, Hu B Abstract The efficient transmission of severe acute respiratory syndrome-2 coronavirus (SARS-CoV-2) from patients to health care workers or family members has been...
pubmed: health technology
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Adjustment Disorder in Female Breast Cancer Patients: Prevalence and Its Accessory Symptoms.
Related ArticlesAdjustment Disorder in Female Breast Cancer Patients: Prevalence and Its Accessory Symptoms. Curr Med Sci. 2020 May 30;: Authors: Tang HY, Xiong HH, Deng LC, Fang YX, Zhang J, Meng H Abstract Women diagnosed with breast cancer may have serious psychological problems and will suffer from adjustment disorder (AjD). We investigated the prevalence of AjD in female breast cancer patients who were diagnosed within 1 year and examined the severe...
pubmed: health technology
18h
Associations of Plasma Copper, Magnesium, and Calcium Levels with Blood Pressure in Children: a Cross-sectional Study.
Related ArticlesAssociations of Plasma Copper, Magnesium, and Calcium Levels with Blood Pressure in Children: a Cross-sectional Study. Biol Trace Elem Res. 2020 May 30;: Authors: Chen G, Li Y, Deng G, Shrestha S, Chen F, Wei Y, Huang Z, Pan J, Zhang Z Abstract Studies of the relationship of copper (Cu), magnesium (Mg), and calcium (Ca) levels with blood pressure in children are limited. This cross-sectional study included 443 children aged 6-9 years...
pubmed: health technology
18h
In silico validation of electrocardiographic imaging to reconstruct the endocardial and epicardial repolarization pattern using the equivalent dipole layer source model.
Related ArticlesIn silico validation of electrocardiographic imaging to reconstruct the endocardial and epicardial repolarization pattern using the equivalent dipole layer source model. Med Biol Eng Comput. 2020 May 31;: Authors: van der Waal J, Meijborg V, Schuler S, Coronel R, Oostendorp T Abstract The solution of the inverse problem of electrocardiology allows the reconstruction of the spatial distribution of the electrical activity of the heart from...
pubmed: health technology
18h
Efficient removal of antibiotic oxytetracycline from water using optimized montmorillonite-supported zero-valent iron nanocomposites.
Related ArticlesEfficient removal of antibiotic oxytetracycline from water using optimized montmorillonite-supported zero-valent iron nanocomposites. Environ Sci Pollut Res Int. 2020 May 30;: Authors: Tran ML, Deng SW, Fu CC, Juang RS Abstract In this study, montmorillonite-supported nanoscaled zero-valent iron (Mt-nZVI) composites were fabricated using a facile liquid-phase reduction method to avoid serious agglomeration of nZVI particles in suspensions...
pubmed: health technology
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Investigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4.
Related ArticlesInvestigation of the effects of urea cycle amino acids on the expression of ALB and CEBPB in the human hepatocellular carcinoma cell line FLC-4. Hum Cell. 2020 May 30;: Authors: Fujimi TJ, Mezaki Y, Masaki T, Tajima A, Nakamura M, Yoshikawa A, Murai N, Aizawa M, Kojima S, Matsumoto Y, Aizaki H, Matsuura T Abstract Cell lines are powerful tools for research into liver function at the molecular level. However, they are generally unsuitable...
pubmed: health technology
18h
Peri-prostatic adipose tissue measurements using MRI predict prostate cancer aggressiveness in men undergoing radical prostatectomy.
Related ArticlesPeri-prostatic adipose tissue measurements using MRI predict prostate cancer aggressiveness in men undergoing radical prostatectomy. J Endocrinol Invest. 2020 May 30;: Authors: Zhai T-, Hu L-, Ma W-, Chen X, Luo M, Jin L, Zhou Z, Liu X, Kang Y, Kang Y-, Zhang J-, Liu H, Lu J-, Yao X-, Ye L Abstract OBJECTIVES: To evaluate the effect of peri-prostatic adipose tissue (PPAT) measurements using preoperative MRI on the prediction of prostate...
pubmed: health technology
18h
Discovery of a transcriptomic core of genes shared in 8 primary retinoblastoma with a novel detection score analysis.
Related ArticlesDiscovery of a transcriptomic core of genes shared in 8 primary retinoblastoma with a novel detection score analysis. J Cancer Res Clin Oncol. 2020 May 30;: Authors: Alvarez-Suarez DE, Tovar H, Hernández-Lemus E, Orjuela M, Sadowinski-Pine S, Cabrera-Muñoz L, Camacho J, Favari L, Hernández-Angeles A, Ponce-Castañeda MV Abstract PURPOSE: Expression microarrays are powerful technology that allows large-scale analysis of RNA profiles in...
pubmed: health technology
18h
Comparative analysis of a Thai congenital-Zika-syndrome-associated virus with a Thai Zika-fever-associated virus.
Related ArticlesComparative analysis of a Thai congenital-Zika-syndrome-associated virus with a Thai Zika-fever-associated virus. Arch Virol. 2020 May 30;: Authors: Jitsatja A, Ramphan S, Promma P, Kuadkitkan A, Wikan N, Uiprasertkul M, Phatihattakorn C, Smith DR Abstract In this study, we compared the characteristics of two strains of Zika virus (ZIKV) isolated in Thailand, one isolated from a febrile patient and one isolated from tissues of a fetus...
pubmed: health technology
18h
Sorghum Pasta and Noodles: Technological and Nutritional Aspects.
Related ArticlesSorghum Pasta and Noodles: Technological and Nutritional Aspects. Plant Foods Hum Nutr. 2020 May 30;: Authors: Palavecino PM, Curti MI, Bustos MC, Penci MC, Ribotta PD Abstract Sorghum is a major cereal crop with various agronomic advantages, contains health-promoting compounds and is gluten-free. There is a growing tendency to use sorghum in pasta and noodle formulations, which are among the most widely consumed products in the world,...
pubmed: health technology
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Binding modes of cabazitaxel with the different human β-tubulin isotypes: DFT and MD studies.
Related ArticlesBinding modes of cabazitaxel with the different human β-tubulin isotypes: DFT and MD studies. J Mol Model. 2020 May 30;26(6):162 Authors: Zhu L, Zhang C, Lü X, Song C, Wang C, Zhang M, Xie Y, Schaefer HF Abstract Taxanes (paclitaxel, docetaxel, cabazitaxel) are anticancer drugs as microtubule inhibitors. Following our previous studies on paclitaxel and docetaxel, in this work, we examine cabazitaxel and compare these three taxenes. The...
pubmed: health technology
18h
Para-aortic lymph node tracing and dissection in advanced gastric cancer: Effectiveness of carbon nanoparticles injection through the no. 12b lymph node.
Related ArticlesPara-aortic lymph node tracing and dissection in advanced gastric cancer: Effectiveness of carbon nanoparticles injection through the no. 12b lymph node. J Cancer Res Ther. 2020;16(2):238-242 Authors: Mu G, Huang Y, Wei C, Chen Z, Wu X, Qin X, Zeng Y Abstract Background and Objectives: The relative effectiveness of tracers in guiding para-aortic lymph node dissection (PAND) in advanced gastric cancer is undefined. In this single-center,...
pubmed: health technology
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