Clinicopathological analysis of lymphomatoid granulomatosis
Author(s): GUO Pei-min, YUAN Shu-hong, Department of Pathology, Dezhou People's Hospital, Department of Gynaecology and Obstetrics, Dezhou People's Hospital
Journal: Clinical Medicine, Year 2015 , Issue 8 , Page 33-34+128
Keyword: Lymphomatoid granulomatosis; EB virus; Immunohistochemical;
Abstract: Objective To investigate the clinicopathological feature,immunophenotype and differential diagnosis of lymphomatoid granulomatosis. Methods The characteristics of clinicopathology and histopathology of 2 cases of lymphomatoid granulomatosis were observed,with immunophenotype and review of the literatures. Results Two cases of lymphomatoid granulomatosis showed the main lymphoproliferative lesions were vascular damaging,lymphocytes were polymorphic and atypical and were composed of the B cells of EB virus infection and a large number of mixed reactive T cells. Conclusion Lymphomatoid granulomatosis is a rare low-grade malignant lesions,showed changes of histological grading and clinical aggressiveness,associated with the ratio of positive B cells of EB virus. Lymphomatoid granulomatosis can progress to EBV positive diffuse large B cell lymphoma.
http://caod.oriprobe.com/articles/46351751/Clinicopathological_analysis_of_lymphomatoid_granu.htm
Author(s): GUO Pei-min, YUAN Shu-hong, Department of Pathology, Dezhou People's Hospital, Department of Gynaecology and Obstetrics, Dezhou People's Hospital
Journal: Clinical Medicine, Year 2015 , Issue 8 , Page 33-34+128
Keyword: Lymphomatoid granulomatosis; EB virus; Immunohistochemical;
Abstract: Objective To investigate the clinicopathological feature,immunophenotype and differential diagnosis of lymphomatoid granulomatosis. Methods The characteristics of clinicopathology and histopathology of 2 cases of lymphomatoid granulomatosis were observed,with immunophenotype and review of the literatures. Results Two cases of lymphomatoid granulomatosis showed the main lymphoproliferative lesions were vascular damaging,lymphocytes were polymorphic and atypical and were composed of the B cells of EB virus infection and a large number of mixed reactive T cells. Conclusion Lymphomatoid granulomatosis is a rare low-grade malignant lesions,showed changes of histological grading and clinical aggressiveness,associated with the ratio of positive B cells of EB virus. Lymphomatoid granulomatosis can progress to EBV positive diffuse large B cell lymphoma.
http://caod.oriprobe.com/articles/46351751/Clinicopathological_analysis_of_lymphomatoid_granu.htm
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